4-[(6-Bromo-4-phenylquinazolin-2-yl)amino]benzoic acid CAS 332102-08-6
| CAS No. | 332102-08-6 |
| Molecular Formula | C21H14BrN3O2 |
| Molecular Weight | 420.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-[(6-Bromo-4-phenylquinazolin-2-yl)amino]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-[(6-Bromo-4-phenylquinazolin-2-yl)amino]benzoic acid (CAS 332102-08-6) is a high-purity analytical reference standard with the molecular formula C21H14BrN3O2 and a molecular weight of 420.26 g/mol.
4-[(6-Bromo-4-phenylquinazolin-2-yl)amino]benzoic acid (C21H14BrN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H14BrN3O2 |
| Molecular Weight | 420.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 3-((6-Bromo-4-phenylquinazolin-2-yl)amino)benzoic acid (CAS 330850-57-2)
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Recommended Standards
- 7-[(E)-2-[(2,5-Difluorophenyl)methylidene]hydrazin-1-yl]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 338962-14-4)
- 2-(3-Bromophenyl)-4-methyl-6-(phenylamino)quinazoline-5,8-dione (CAS 61416-86-2)
- 446286-06-2 2-(Methylsulfanyl)-4-(tributylstannyl)-1,3-thiazole DTXSID00676709 (CAS 446286-06-2)
- 2-(Benzo[d][1,3]dioxol-5-yl)-3-((4-bromophenyl)amino)-1H-inden-1-one (CAS 1023875-63-9)
- (S)-2-Amino-2-(p-tolyl)ethanol (CAS 327183-90-4)
- 1-Fluoro-3-phenyl-2-propylamine Hydrochloride (CAS 77184-98-6)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-4-(phenylsulfonyl)butanamide (CAS 338420-80-7)
- 2-(4-(Difluoromethyl)-5-hydroxy-6-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805611-96-4)
- Benzyl ((1-((S)-2-amino-3-methylbutanoyl)piperidin-2-yl)methyl)(ethyl)carbamate (CAS 1354023-82-7)
- Tyr-ACTH (4-9) (CAS 129813-57-6)
- 1-(2,6-Dimethylphenyl)-3-phenylpropan-1-one (CAS 898764-30-2)
- Tert-butyl 5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (CAS 1883598-68-2)
- (5,5-dimethyloxolan-2-yl)methanamine hydrochloride (CAS 1803592-77-9)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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