3-Benzoyl-4-chlorobenzene-1-sulfonyl chloride CAS 33211-56-2
| CAS No. | 33211-56-2 |
| Molecular Formula | C13H8Cl2O3S |
| Molecular Weight | 315.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Benzoyl-4-chlorobenzene-1-sulfonyl chloride (CAS 33211-56-2), molecular formula C13H8Cl2O3S and molecular weight 315.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Benzoyl-4-chlorobenzene-1-sulfonyl chloride (C13H8Cl2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2O3S |
| Molecular Weight | 315.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Benzoyl Standards
- 2-Benzoyl-4-chlorobenzenesulfonyl chloride (CAS 19562-55-1)
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- 5-Benzoyl-4-(4-methylpiperazin-1-yl)isoxazole-3-carboxamide (CAS 647862-54-2)
- Methyl [benzoyl(3-formyl-2,5-dimethyl-1h-pyrrol-1-yl)amino]acetate (CAS 880062-11-3)
- N-(3-Benzoyl-5-chlorothiophen-2-yl)-2-chloroacetamide (CAS 30199-09-8)
- 1-(1-benzoyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-chloroethan-1-one (CAS 1461707-22-1)
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Recommended Standards
- 2-[5-(2,4-Dichlorobenzoyl)thiophen-2-yl]acetic acid (CAS 339014-63-0)
- 4-(1,3,2-Dioxaborolan-2-yl)-N,N-diphenylaniline (CAS 402488-98-6)
- 1-[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrrolidine-2,5-dione (CAS 2096997-21-4)
- 4-Fluoro-N-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 2821763-93-1)
- 5-Fluoro-3-pyrrolidin-1-ylbenzaldehyde (CAS 1692606-40-8)
- (1E)-3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one (CAS 1393342-06-7)
- 4-[4-(4-chlorophenyl)piperazin-1-yl]-4-oxobutanoic acid (CAS 540521-73-1)
- 1-(2,6-Dichlorobenzyl)-N-(2-(dimethylamino)ethyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338754-98-6)
- N-(2-phenoxyethyl)cyclopropanamine (CAS 16690-27-0)
- 2-(2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-1H-pyrrol-1-yl)ethanamine (CAS 1707594-73-7)
- Thioctic acid Impurity 97 (CAS CATO-C4X-152697)
- myo-Inositol hexasulfate hexapotassium salt (CAS 28434-25-5)
- (S)-1-METHYL-5-VINYLPYRROLIDIN-2-ONE (CAS 122663-18-7)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
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