2-(Fmoc-amino)-4-chlorobenzoic acid CAS 332121-92-3
| CAS No. | 332121-92-3 |
| Molecular Formula | C22H16ClNO4 |
| Molecular Weight | 393.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Fmoc-amino)-4-chlorobenzoic acid (CAS 332121-92-3), molecular formula C22H16ClNO4 and molecular weight 393.82 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Fmoc-amino)-4-chlorobenzoic acid (C22H16ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16ClNO4 |
| Molecular Weight | 393.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- N-Fmoc-4-amino-2-chlorobenzoic acid (CAS 186320-13-8)
- N-Fmoc-5-amino-2-chlorobenzoic acid (CAS 186320-16-1)
- 2-(Fmoc-amino)-5-chlorobenzoic Acid (CAS 332121-90-1)
- Fmoc-β-(2-thienyl)-D-Ala-OH (CAS 201532-42-5)
- N-Fmoc-(3S)-3-amino-3-cyclohexylpropanoic acid (CAS 1260614-86-5)
- N-Fmoc-N-(cyclohexylmethyl)-glycine (CAS 1374785-49-5)
- Fmoc-n-methyl-tranexamic acid (CAS 173690-50-1)
- Fmoc-L-2-methylamino-7-octenoic acid (CAS 1808268-11-2)
Recommended Standards
- 2-(4-Chlorophenyl)-1-((4-methylbenzyl)oxy)-6-nitro-1H-benzo[d]imidazole (CAS 282523-17-5)
- 2-(3-Chlorophenyl)-1-((4-methylbenzyl)oxy)-6-nitro-1H-benzo[d]imidazole (CAS 303149-38-4)
- 2-Bromo-3-(bromomethyl)-4-fluoro-1-iodobenzene (CAS 2092531-09-2)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-chlorobenzoic acid (CAS 914348-17-7)
- 1-(1H-benzo[d]imidazol-2-yl)-N-ethylethan-1-amine (CAS 860188-68-7)
- 3-bromo-8-methoxyimidazo[1,2-a]pyrazine (CAS 91775-62-1)
- 3-(Thiophen-3-yl)imidazo[1,2-a]pyrazin-8-amine (CAS 825630-41-9)
- 3,3,3-Trifluoro-2-(quinolin-8-yloxy)propan-1-amine (CAS 886764-58-5)
- Amino(2,5-dimethylphenyl)acetic acid (CAS 293330-04-8)
- (Rac)-Baxdrostat (CAS 1428652-15-6)
- (4-(Butyramidomethyl)phenyl)boronic acid (CAS 2246765-26-2)
- 1-(5-Chloro-2-(ethylthio)phenyl)-N-methylmethanamine (CAS 1368279-10-0)
- 1-Azaspiro[4.5]decane-2,8-dione (CAS 749861-03-8)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
Why CATO?
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