N-(3-chlorophenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide CAS 332162-79-5
| CAS No. | 332162-79-5 |
| Molecular Formula | C26H17Cl2N3OS |
| Molecular Weight | 490.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-chlorophenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-(3-chlorophenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332162-79-5), a certified reference material (molecular formula C26H17Cl2N3OS, MW 490.40 g/mol) for analytical method development and quality control.
The molecular framework of N-(3-chlorophenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (C26H17Cl2N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H17Cl2N3OS |
| Molecular Weight | 490.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-phenylacetamide (CAS 332372-17-5)
- 2-((4,6-Bis(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-phenylacetamide (CAS 332385-63-4)
- N-(2-chlorophenyl)-2-((4-(4-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332385-53-2)
- N-(4-chlorophenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332128-35-5)
- (5-{[(4-chlorophenyl)methyl]sulfanyl}-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl N-(4-chlorophenyl)carbamate (CAS 318469-49-7)
- 2-((2-((4-Chlorophenyl)sulfonyl)ethyl)thio)-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 625368-12-9)
- 3-((4-Chlorophenyl)sulfonyl)-2-(cyclohexylsulfonyl)-4-methyl-6-phenylpyridine (CAS 339103-37-6)
- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide (CAS 476483-85-9)
Recommended Standards
- 3-Amino-N-(3-chlorophenyl)-6-(4-chlorophenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 334503-98-9)
- Clopidogrel EP impurity D (CAS 1421283-60-4)
- 3-Amino-N-(2-chlorophenyl)-4-(4-chlorophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332385-54-3)
- [(2R,3R,4S,5R,6S)-6-[4-(3,4-dihydroxyphenyl)-7-hydroxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate (CAS 1112383-48-8)
- Methyl 2'-hydroxy-[1,1'-biphenyl]-3-carboxylate (CAS 92254-28-9)
- 2,4-Diamino-6-methylpyrimidine-5-carbonitrile (CAS 7466-13-9)
- 3,3-Difluorotetrahydro-2H-pyran-4-amine hydrochloride (CAS 2244040-19-3)
- Ethyl 2-(3-nitrobenzylidene)-3-oxobutanoate (CAS 39562-16-8)
- (2S,3R,4S,5S)-5-((R)-1-Azido-2-(pivaloyloxy)ethyl)tetrahydrofuran-2,3,4-triyl tris(2,2-dimethylpropanoate) (CAS 226877-06-1)
- 4-Bromopiperidine hydrochloride, 95% (CAS 1001397-43-8)
- Phosphoric acid, lanthanum(3+) salt (CAS 13778-59-1)
- 4-Methylthiophen-2-amine oxalate (CAS 14893-94-8)
- 3-Chloro-4-fluoro-5-methylphenol (CAS 1784533-88-5)
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