6-Bromo-4-(2-chlorophenyl)-2-methoxyquinazoline CAS 332173-47-4

Purity 97%+In StockPharmaceutical Standards
CAS No.332173-47-4
Molecular FormulaC15H10BrClN2O
Molecular Weight349.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-4-(2-chlorophenyl)-2-methoxyquinazoline CAS 332173-47-4 chemical structure

Description

6-Bromo-4-(2-chlorophenyl)-2-methoxyquinazoline (C15H10BrClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies 6-Bromo-4-(2-chlorophenyl)-2-methoxyquinazoline (CAS 332173-47-4), a certified reference material (molecular formula C15H10BrClN2O, MW 349.61 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H10BrClN2O
Molecular Weight349.61 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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