3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide CAS 332376-52-0
| CAS No. | 332376-52-0 |
| Molecular Formula | C27H19Cl2N3O2S |
| Molecular Weight | 520.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide.
3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332376-52-0), molecular formula C27H19Cl2N3O2S and molecular weight 520.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (C27H19Cl2N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H19Cl2N3O2S |
| Molecular Weight | 520.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(2,3-dichlorophenyl)-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332376-21-3)
- 3-Amino-N-(2,5-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332175-75-4)
- 3-Amino-N-(2,5-dichlorophenyl)-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332175-76-5)
- 3-Amino-N-(2-chlorophenyl)-4-(4-chlorophenyl)-6-(4-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332385-56-5)
- (S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-((4-nitrobenzyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid (CAS 6803-19-6)
- Methyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(2-fluoro-5-methoxyphenyl)-4H-pyran-3-carboxylate (CAS 445384-60-1)
- 2-Amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-3,5-pyridinedicarbonitrile 544417-40-5 (CAS 544417-40-5)
- 3-Amino-2,4,6-triiodobenzoic Acid (50 mg) (CAS 3119-15-1)
Recommended Standards
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 337936-16-0)
- 1-[3,5-Bis(trifluoromethyl)phenyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796922-71-8)
- Ledipasvir Impurity 48 (CAS CATO-C4X-331348)
- Aciclovir Impurity 35 (CAS CATO-C4X-101035)
- 6-Bromo-2-iodo-3-methoxypyridine (CAS 2140305-26-4)
- 8-(Tert-butyl) 2-methyl (1R,2S,5R)-8-azabicyclo[3.2.1]Octane-2,8-dicarboxylate (CAS 190322-72-6)
- 1-Cyclopropyl-1-(3,4-dichlorophenyl)ethan-1-ol (CAS 1379310-89-0)
- 2-Bromo-6-fluoro-4-methylbenzenethiol (CAS 1208075-32-4)
- 1-Benzyl 5-(tert-butyl) ((benzyloxy)carbonyl)-L-glutamate (CAS 3967-18-8)
- 2-Bromo-3-chlorobenzamide (CAS 1208076-32-7)
- 6-Chloro-N-(4-methyl-3-nitrophenyl)pyridazin-3-amine (CAS 61471-96-3)
- 4-(1,4,6,7-Tetrahydropyrano[4,3-c]pyrazol-3-yl)aniline (CAS 2138570-31-5)
- 4-ethoxy-2-methylbenzene-1-sulfonamide (CAS 68978-32-5)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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