3-Amino-N-(2,5-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide CAS 332175-75-4
| CAS No. | 332175-75-4 |
| Molecular Formula | C27H19Cl2N3O2S |
| Molecular Weight | 520.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Amino-N-(2,5-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332175-75-4), a certified reference material (molecular formula C27H19Cl2N3O2S, MW 520.43 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-N-(2,5-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (C27H19Cl2N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Amino-N-(2,5-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H19Cl2N3O2S |
| Molecular Weight | 520.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332376-52-0)
- 3-Amino-N-(2,3-dichlorophenyl)-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332376-21-3)
- 3-Amino-N-(2,5-dichlorophenyl)-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332175-76-5)
- 3-Amino-N-(2-chlorophenyl)-4-(4-chlorophenyl)-6-(4-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332385-56-5)
- (S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-((4-nitrobenzyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid (CAS 6803-19-6)
- Methyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(2-fluoro-5-methoxyphenyl)-4H-pyran-3-carboxylate (CAS 445384-60-1)
- 2-Amino-6-[[[2-(4-chlorophenyl)-4-thiazolyl]methyl]thio]-4-[4-(2-hydroxyethoxy)phenyl]-3,5-pyridinedicarbonitrile 544417-40-5 (CAS 544417-40-5)
- 3-Amino-2,4,6-triiodobenzoic Acid (50 mg) (CAS 3119-15-1)
Recommended Standards
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 337936-16-0)
- N-(4,4-dibromo-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)pivalamide (CAS 439092-50-9)
- 1-[3,5-Bis(trifluoromethyl)phenyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796922-71-8)
- N-(5-Chloro-2-methoxyphenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332164-03-1)
- 4-Chloro-2-(1-chloroethyl)-6-cyclobutylpyrimidine (CAS 1427023-92-4)
- 4-(Dimethoxymethyl)pyridin-2-amine (CAS 889945-19-1)
- 5-Methyl-4-(morpholinomethyl)isoxazole-3-carboxylic acid hydrochloride (CAS 1177341-15-9)
- 1,2,4-trimethyl-1H-pyrrole-3-carbaldehyde (CAS 1142201-80-6)
- 4-(Difluoromethyl)pyridine stabilized over potassium carbonate 4-Difluoromethylpyridine 82878-62-4 (CAS 82878-62-4)
- 3-Methyl-4-(trifluoromethyl)benzoic acid (CAS 871571-29-8)
- 2-((Allyloxy)methyl)tetrahydrofuran (CAS 175668-89-0)
- 4-Bromo-5-chloro-2-(trifluoromethyl)acetophenone (CAS 1807114-58-4)
- Voriconazole Impurity 8 (CAS 83603-04-7)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
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