6-Fluoro-2-(thiophen-2-yl)quinoline-4-carboxylic acid CAS 33289-53-1
| CAS No. | 33289-53-1 |
| Molecular Formula | C14H8FNO2S |
| Molecular Weight | 273.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Fluoro-2-(thiophen-2-yl)quinoline-4-carboxylic acid (CAS 33289-53-1) is a high-purity analytical reference standard with the molecular formula C14H8FNO2S and a molecular weight of 273.28 g/mol.
The molecular framework of 6-Fluoro-2-(thiophen-2-yl)quinoline-4-carboxylic acid (C14H8FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Fluoro-2-(thiophen-2-yl)quinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8FNO2S |
| Molecular Weight | 273.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- 4-Fluoro-3-(pyrrolidine-1-sulfonyl)benzoic acid (CAS 361157-90-6)
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Recommended Standards
- 6-Butylquinoline-2,3-dicarboxylic acid (CAS 92513-53-6)
- 6-p-Anisidino-m-anisic Acid (CAS 56980-14-4)
- 6-(Benzyloxy)-3-(difluoromethyl)-1H-indole (CAS 2149598-55-8)
- 7-(Benzyloxy)-3-(difluoromethyl)-1H-indole (CAS 2149590-56-5)
- 3-Fluoro-1-isobutylpyrrolidin-2-one (CAS 522665-42-5)
- 5-Bromo-2-methoxy-3-methylbenzonitrile (CAS 1211483-68-9)
- 2-Ethylthiomorpholine (CAS 30188-20-6)
- Trimethyl(2,4,5-trimethylphenyl)silane (CAS 140435-95-6)
- (S)-2-((6R,8R)-7,7-Dimethyl-5,6,7,8-tetrahydro-6,8-methanoquinolin-2-yl)-4-phenyl-4,5-dihydrooxazole (CAS 1027754-31-9)
- Tert-butyl (4-amino-5,5,5-trifluoropentyl)carbamate (CAS 1354950-30-3)
- 3-Aceto-2-hydroxybiphenyl (CAS 21424-82-8)
- spiro[7H-furo[3,4-b]pyridine-5,4'-piperidine] (CAS 1036408-86-2)
- 2-(9H-Purin-6-yl)ethanamine (CAS 89854-22-8)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
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