Ethyl 2-(2-((5-(4-chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate CAS 332934-77-7
| CAS No. | 332934-77-7 |
| Molecular Formula | C23H25ClN4O3S2 |
| Molecular Weight | 505.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-(2-((5-(4-chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate.
Ethyl 2-(2-((5-(4-chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 332934-77-7) is a high-purity analytical reference standard with the molecular formula C23H25ClN4O3S2 and a molecular weight of 505.05 g/mol.
The molecular framework of Ethyl 2-(2-((5-(4-chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (C23H25ClN4O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H25ClN4O3S2 |
| Molecular Weight | 505.05 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- 1-{5-[(4-chlorophenyl)sulfanyl]-4-phenyl-1,3-thiazol-2-yl}-4-(2-methylpropane-2-sulfonyl)-1H-pyrazol-5-amine (CAS 956606-61-4)
- 1-(4-Chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxamide (CAS 288250-47-5)
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Recommended Standards
- 5-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-3-(cyclohexylmethyl)-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1024595-26-3)
- Ivabradine impurity 79 (CAS 2768438-46-4)
- Suvorexant Impurity 7 (CAS CATO-C4X-18127)
- Dysprosium(III) carbonate (CAS 5066-34-2)
- 2-Benzyl-5-chloro-2H-1,2,3-triazole-4-carboxylic acid (CAS 882865-43-2)
- 2-(3-Bromophenyl)-2,2-difluoroacetamide (CAS 1375472-86-8)
- (6-(Diethylamino)pyridin-2-yl)boronic acid (CAS 1310384-32-7)
- 2-(4-Chlorophenyl)-5-(2-propoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 609794-88-9)
- N-(3-Hydrazinyl-1-(4-nitrophenyl)-3-oxoprop-1-en-2-yl)benzamide (CAS 19655-74-4)
- 6-Methyl-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1260381-59-6)
- 2-fluoro-4-hydrazinylbenzonitrile (CAS 129946-64-1)
- tert-Butyl 4-hydroxy-2-methylpiperidine-1-carboxylate (CAS 208046-23-5)
- 4-Fluoro-6-nitroindoline (CAS 1823931-51-6)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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