Ivabradine impurity 79 CAS 2768438-46-4
| CAS No. | 2768438-46-4 |
| Molecular Formula | C27H37ClN2O5 |
| Molecular Weight | 505.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ivabradine impurity 79 (CAS 2768438-46-4) is a certified pharmaceutical impurity reference standard with the molecular formula C27H37ClN2O5 and a molecular weight of 505.05 g/mol.
Structurally, Ivabradine impurity 79 (C27H37ClN2O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 505.05 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H37ClN2O5 |
| Molecular Weight | 505.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ivabradine Standards
- Ivabradine Impurity 13 (CAS 1462470-54-7)
- Ivabradine impurity 80 (CAS CATO-C4X-111980)
- Ivabradine impurity N1 (CAS 2511244-96-3)
- Ivabradine Impurity 14 (CAS CATO-C4X-111914)
- Ivabradine Impurity 42 (CAS 2511244-97-4)
- Ivabradine Impurity 6 (CAS 2253977-80-7)
- Ivabradine Impurity 68 (CAS CATO-C4X-111968)
- Ivabradine impurity 62 (CAS CATO-C4X-111962)
Recommended Standards
- Ethyl 2-(2-((5-(4-chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 332934-77-7)
- 1-{5-[(4-chlorophenyl)sulfanyl]-4-phenyl-1,3-thiazol-2-yl}-4-(2-methylpropane-2-sulfonyl)-1H-pyrazol-5-amine (CAS 956606-61-4)
- 5-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-3-(cyclohexylmethyl)-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1024595-26-3)
- 4,7-Bis(5-bromothiophen-2-yl)benzo[c][1,2,5]selenadiazole (CAS 534591-72-5)
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- Lenalidomide Impurity 74 (CAS CATO-C4X-190374)
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- Antimycin A3 (CAS 522-70-3)
- 4-(3-Aminopropoxy)benzonitrile (CAS 116753-55-0)
- 158579-82-9 2-TRIFLUOROMETHOXY-5-NITROANILINE 5-Nitro-2-(trifluoromethoxy)aniline AS05398 (CAS 158579-82-9)
- 2-((4-Acetamidophenyl)carbamoyl)benzoic acid (CAS 19336-92-6)
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