2-((1H-Pyrrol-2-yl)methylene)malonic acid CAS 33304-33-5
| CAS No. | 33304-33-5 |
| Molecular Formula | C22H27ClN2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-((1H-Pyrrol-2-yl)methylene)malonic acid (CAS 33304-33-5), a certified reference material (molecular formula C22H27ClN2O4HCl, MW 455.38 g/mol) for analytical method development and quality control.
2-((1H-Pyrrol-2-yl)methylene)malonic acid (C22H27ClN2O4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((1H-Pyrrol-2-yl)methylene)malonic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27ClN2O4 HCl |
| Molecular Weight | 455.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 1005214-01-6 {[2-(1H-Pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothien-3-yl]methyl}amine hydrochloride MFCD22123369 (CAS 1005214-01-6)
- 3-[4-(1H-Pyrrol-1-yl)phenyl]-1H-pyrazole (CAS 1007072-92-5)
- 1013752-32-3 4-(1H-Pyrrol-1-ylmethyl)cyclohexanecarboxylic acid MFCD08744282 (CAS 1013752-32-3)
- 3-(1H-Pyrrol-2-yl)-1H-pyrazole (CAS 1019010-39-9)
- 2-(1H-pyrrol-1-yl)pyridin-3-amine (CAS 102064-32-4)
- 4-(4-(1H-pyrrol-1-yl)phenyl)-1H-pyrazol-3-amine (CAS 1024019-01-9)
- 1-(1H-pyrrol-1-yl)cyclohexane-1-carboxylic acid (CAS 1031596-16-3)
- 2-(1H-pyrrol-2-yl)oxazole-5-carbaldehyde (CAS 1033037-45-4)
Recommended Standards
- 2-(4-Chlorophenyl)-5,5-dimethyl-3-(pyrazin-2-yl)thiazolidin-4-one (CAS 89442-18-2)
- 2-(3-Oxobutan-2-yl)-6-(p-tolyl)pyridazin-3(2H)-one (CAS 853333-97-8)
- 3-Methyl-1,4-oxathiane-2,6-dione (CAS 89603-16-7)
- 1H-Carbazole-1,4(9H)-dione (CAS 70377-05-8)
- 3-(sec-Butoxy)-N-[4-(hexyloxy)benzyl]aniline (CAS 1040685-94-6)
- 6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid (CAS 343-10-2)
- 3-Bromo-5-methoxybenzoyl chloride (CAS 1261582-04-0)
- (2E)-1-(5-Bromo-6-methoxynaphthalen-2-yl)-3-(dimethylamino)-2-methylprop-2-en-1-one (CAS 338407-63-9)
- 5-(Chloromethyl)furan-2-carbaldehyde (CAS 1623-88-7)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com