6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid CAS 343-10-2

Purity 97%+In StockPharmaceutical Standards
CAS No.343-10-2
Molecular FormulaC10H6FNO3
Molecular Weight207.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid CAS 343-10-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 207.16 g/mol gives 6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid (CAS 343-10-2), a certified reference material (molecular formula C10H6FNO3, MW 207.16 g/mol) for analytical method development and quality control.

The molecular framework of 6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid (C10H6FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H6FNO3
Molecular Weight207.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms1

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