N-(3-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide CAS 333331-41-2
| CAS No. | 333331-41-2 |
| Molecular Formula | C18H18ClN5OS |
| Molecular Weight | 387.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies N-(3-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 333331-41-2), a certified reference material (molecular formula C18H18ClN5OS, MW 387.89 g/mol) for analytical method development and quality control.
The molecular framework of N-(3-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (C18H18ClN5OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN5OS |
| Molecular Weight | 387.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(3-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618415-76-2)
- N-(3-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482639-89-4)
- N-(4-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573973-86-1)
- N-(5-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618416-00-5)
- N-(5-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618426-69-0)
- N-(5-Chloro-2-methylphenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482639-88-3)
- 2-chloro-N-(5-morpholinosulfonyl-2-pyrrolidin-1-yl-phenyl)acetamide (CAS 565192-30-5)
- N-(5-Chloro-2-methoxyphenyl)-2-(4-(2,3-dimethylphenyl)piperazin-1-yl)acetamide (CAS 890600-38-1)
Recommended Standards
- 2-((4-Amino-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 577985-08-1)
- 2-((3-(4-Chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-N-cyclopentylacetamide (CAS 852373-37-6)
- N-(4-Chlorophenyl)-2-((3-((m-tolylamino)methyl)-1H-1,2,4-triazol-5-yl)thio)acetamide (CAS 247592-60-5)
- 2-((3-(4-Chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-1-(piperidin-1-yl)ethan-1-one (CAS 852373-01-4)
- 3-((4-Fluorobenzyl)thio)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 896686-81-0)
- (R)-methyl 2-(1-(2-(2-ethoxyethylamino)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoate (CAS 1173900-36-1)
- (3S,4R)-tert-Butyl 3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1932246-33-7)
- 7-Bromo-1,1,1,2,2,3,3-heptafluoroheptane (CAS 1391033-22-9)
- (R)-5-(Chloromethyl)pyrrolidin-2-one (CAS 138541-53-4)
- 3,6-Diisopropylpyridazine (CAS 865076-17-1)
- N-(2,4-Dimethoxybenzyl)-5-fluoro-N-(6-fluoropyridin-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-6-sulfonamide (CAS 1607485-79-9)
- 3-Amino-4-hydroxy-N-phenylbenzenesulfonamide (CAS 80-20-6)
- (4-Oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)thiourea (CAS 865659-26-3)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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