N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-fluorobenzamide CAS 333343-48-9
| CAS No. | 333343-48-9 |
| Molecular Formula | C11H8FN3O3 |
| Molecular Weight | 249.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-fluorobenzamide.
N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-fluorobenzamide (CAS 333343-48-9), molecular formula C11H8FN3O3 and molecular weight 249.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-fluorobenzamide (C11H8FN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-fluorobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8FN3O3 |
| Molecular Weight | 249.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-fluorobenzamide (CAS 424799-26-8)
- 2-(1-Ethyl-2,4-dioxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4H)-yl)acetic acid (CAS 1708080-05-0)
- 2-(3-Ethyl-2,4-dioxo-3,4-dihydropyrido[2,3-d]pyrimidin-1(2H)-yl)acetic acid (CAS 1713461-77-8)
- 2,4-Dioxo-1-propyl-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 929972-72-5)
- 4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid (CAS 199167-79-8)
- 2-(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-ylamino)-4-methyl-pentanoic acid (CAS 792893-05-1)
- 4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanethioamide (CAS 41306-76-7)
- 4,7-Dioxo-7-(p-tolyl)heptanoic acid (CAS 522663-97-4)
Recommended Standards
- 3,5-Bis(trifluoromethyl)benzylamine 3,5-bis(trifluoromethyl)benzyl amine 3, 5-bis(trifluoromethyl)benzylamine 3,5-di(trifluoromethyl)benzylamine 3,5-bis-trifluoromethyl-benzylamine 3,5-ditrifluoromethylbenzylamine 3,5-bis(trifluoromethyl) benzylamine 3,5-Bis(trifluoromethyl)benzenemethanamine [3,5-Bis(trifluoromethyl)phenyl]methanamine [[3,5-Bis(trifluoromethyl)phenyl]methyl]amine 85068-29-7 (CAS 85068-29-7)
- Diphenyl phosphoramidate (CAS 2015-56-7)
- Creatine impurity 21 (CAS CATO-C4X-120921)
- 5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide (CAS 56563-17-8)
- 2-Fluoro-5-hydroxy-N-methoxybenzamide (CAS 1881291-67-3)
- 1,1-Dimethylethyl N-[1-(2-nitrophenyl)-4-piperidinyl]carbamate (CAS 1023594-62-8)
- D-Lyxose-2-13C (CAS 83379-39-9)
- 2-Chloro-4-methoxy-3,5-dimethylpyridine (CAS 110464-98-7)
- Revefenacin Impurity 63 (CAS CATO-C4X-203163)
- Methyl 2-amino-2-(2,4-dimethylphenyl)acetate (CAS 1218698-66-8)
- N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)benzamide (CAS 72409-43-9)
- 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one (CAS 1219130-55-8)
- n-(4-Hydroxy-3-(1-mercaptoethyl)phenyl)butyramide (CAS 1039964-25-4)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com