5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide CAS 56563-17-8
| CAS No. | 56563-17-8 |
| Molecular Formula | C11H8FN3O3 |
| Molecular Weight | 249.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide (CAS 56563-17-8) is a high-purity analytical reference standard with the molecular formula C11H8FN3O3 and a molecular weight of 249.20 g/mol.
5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide (C11H8FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-2,4-dioxo-N-phenyl-3,4-dihydropyrimidine-1(2H)-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8FN3O3 |
| Molecular Weight | 249.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- (R)-4-fluoro-2-(pyrrolidin-2-yl)-5-(trifluoromethyl)phenol (CAS 1213045-34-1)
- (R)-2-(3-fluoro-4-(trifluoromethoxy)phenyl)pyrrolidine (CAS 1213113-14-4)
- (S)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol (CAS 1213378-15-4)
- (S)-4-fluoro-2-(pyrrolidin-2-yl)-5-(trifluoromethyl)phenol (CAS 1213538-24-9)
- (S)-2-(3-fluoro-4-(trifluoromethoxy)phenyl)pyrrolidine (CAS 1213874-96-4)
- (R)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol (CAS 1213948-46-9)
- (R)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272736-42-1)
- (S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272753-26-0)
Recommended Standards
- 4-((4-Fluorophenyl)carbamoyl)-1H-imidazole-5-carboxylic acid (CAS 575497-25-5)
- Diphenyl phosphoramidate (CAS 2015-56-7)
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- N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-fluorobenzamide (CAS 424799-26-8)
- 3-Oxo-3-(1-(phenylsulfonyl)-1H-indol-2-yl)propanenitrile (CAS 1265234-00-1)
- Methyl 4H-furo[3,2-b]pyrrole-5-carboxylate (CAS 77484-99-2)
- 4-Amino-1-ethyl-3-methyl-1H-pyrazole-5-carboxamide (CAS 89239-62-3)
- 2-Chloro-6-fluoro isopropoxybenzene (CAS 1369889-41-7)
- 1-Chloropropylbenzene (CAS 934-11-2)
- 5-(Trifluoromethyl)benzo[d]thiazole-2-carboxylic acid (CAS 219648-60-9)
- 4-Bromo-6-fluoro-2-methyl-2H-indazole (CAS 1425932-77-9)
- 2-(propan-2-yl)oxetan-3-amine (CAS 2227206-40-6)
- sodium 2-(3-methoxypyridin-2-yl)butanoate (CAS 1803588-08-0)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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