1-((4-Chlorophenyl)sulfonyl)-4-(pyridin-2-yl)piperazine CAS 333440-99-6
| CAS No. | 333440-99-6 |
| Molecular Formula | C15H16ClN3O2S |
| Molecular Weight | 337.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-((4-Chlorophenyl)sulfonyl)-4-(pyridin-2-yl)piperazine (CAS 333440-99-6), molecular formula C15H16ClN3O2S and molecular weight 337.82 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 1-((4-Chlorophenyl)sulfonyl)-4-(pyridin-2-yl)piperazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-((4-Chlorophenyl)sulfonyl)-4-(pyridin-2-yl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16ClN3O2S |
| Molecular Weight | 337.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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- 2-[(2-Chlorophenyl)methanesulfonyl]-N-methyl-N-phenylacetamide (CAS 339110-03-1)
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- 4-(4-Chlorophenyl)-3-(2,2-dimethoxyethyl)-5-(prop-2-yn-1-ylthio)-4H-1,2,4-triazole (CAS 303995-44-0)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-morpholinoacetamide (CAS 92494-47-8)
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Recommended Standards
- Ethyl 2-(2-chloroacetamido)-4-(p-tolyl)thiophene-3-carboxylate (CAS 138098-81-4)
- 1-(3-(6-Chloro-2H-chromen-3-yl)-1,2,4-oxadiazol-5-yl)-3-(methylthio)propan-1-amine (CAS 1269534-64-6)
- Tosyl-D-phenylalaninoyl chloride (CAS 1266583-91-8)
- 4-Amino-N-(benzo[d]thiazol-2-yl)benzenesulfonamide (CAS 6138-01-8)
- 1-(Quinazolin-4-yl)azetidine-3-carboxylic acid (CAS 1365988-06-2)
- 4-(3,4-Dihydroxyphenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 5985-95-5)
- 3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile (CAS 343375-35-9)
- [2-(Propan-2-yloxy)pyridin-4-yl]methanamine (CAS 1016752-74-1)
- 3-(2,4-Dimethylphenoxy)propanoic acid (CAS 15904-03-7)
- (1-TOsyl-1h-pyrrol-3-yl)methanol (CAS 634612-37-6)
- Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate (CAS 58610-66-5)
- 3,4-Dibromo-1H-indazol-6-ol (CAS 887568-91-4)
- methyl 1-(4-chlorobenzoyl)-4-piperidinecarboxylate (CAS 349614-05-7)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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