1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanecarboxylic Acid CAS 334477-30-4
| CAS No. | 334477-30-4 |
| Molecular Formula | C12H8F6O2 |
| Molecular Weight | 298.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 298.18 g/mol gives 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanecarboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanecarboxylic Acid (CAS 334477-30-4) is a high-purity analytical reference standard with the molecular formula C12H8F6O2 and a molecular weight of 298.18 g/mol.
1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanecarboxylic Acid (C12H8F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanecarboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8F6O2 |
| Molecular Weight | 298.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Bis Standards
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1H-imidazole-4-carboxylic acid (CAS 1707566-78-6)
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1H-pyrazole-3-carboxylic acid (CAS 1708013-81-3)
- 3,5-BIs(trifluoromethyl)cinnamic acid methyl ester (CAS 705250-77-7)
- 2,5-Bis(trifluoromethyl)-1H-benzo[d]imidazole-6-carboxylic acid (CAS 1309602-77-4)
- 2-(3,5-Bis(trifluoromethyl)phenyl)piperazine (CAS 1060807-69-3)
- 1-(3,5-Bis(trifluoromethyl)phenyl)piperazine (CAS 16172-96-6)
- Ethyl2-(((trifluoromethyl)sulfonyl)oxy)benzoate (CAS 179538-97-7)
- (R)-2-(4-(((Trifluoromethyl)sulfonyl)oxy)phenyl)propanoic acid (CAS 533931-60-1)
Recommended Standards
- 1-[(3-bromophenyl)methyl]piperidine-3-carboxylic acid (CAS 896046-55-2)
- 1-Boc-6-bromoindoline (CAS 214614-97-8)
- 1-(4-Bromobenzyl)piperidine-4-carboxylic acid (CAS 733797-83-6)
- 2-(2-Ethoxynaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246703-71-7)
- (S)-5-Methylpiperazin-2-one hydrochloride (CAS 1609388-47-7)
- 4-(4-Fluorophenyl)-3-(methoxymethyl)-1H-pyrazol-5-amine (CAS 955574-51-3)
- (2E)-3-(2H-1,3-Benzodioxol-5-yl)-N-(4-phenoxyphenyl)prop-2-enamide (CAS 298215-73-3)
- 1-(Carboxymethyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1379181-19-7)
- 4-(Dimethylamino)-N-(5-phenyl-1H-pyrazolo[3,4-c]pyridazin-3-yl)butanamide (2R,3R)-2,3-dihydroxysuccinate (CAS 1858224-32-4)
- 1-(2-Hydroxyethyl)-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 1510309-88-2)
- (R)-1-(3-(Ethyl(2-hydroxyethyl)amino)pyrrolidin-1-yl)ethanone (CAS 1354003-48-7)
- 1-(2-Chloro-6-fluorobenzyl)-4-(4-fluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-37-7)
- 2-(tert-Butoxy)ethanamine (CAS 88615-68-3)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com