2-Phenyl-5-(trifluoromethyl)-1H-imidazole CAS 33469-36-2
| CAS No. | 33469-36-2 |
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Phenyl-5-(trifluoromethyl)-1H-imidazole (C10H7F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Phenyl-5-(trifluoromethyl)-1H-imidazole (CAS 33469-36-2) is a high-purity analytical reference standard with the molecular formula C10H7F3N2 and a molecular weight of 212.17 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Phenyl-5-(trifluoromethyl)-1H-imidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Phenyl Standards
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Recommended Standards
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- 2-[4-(Trifluoromethyl)phenyl]imidazole (CAS 34898-30-1)
- 3-(1H-Pyrrol-1-yl)-4-(trifluoromethyl)pyridine (CAS 288161-05-7)
- Methyl 2-((9-methyl-5H-thiochromeno[4,3-d]pyrimidin-2-yl)thio)acetate (CAS 478246-78-5)
- Ethyl [(5-chloro-1,3-benzoxazol-2-yl)thio]acetate (CAS 84829-54-9)
- 5,5,5-Trifluoro-2-hydroxypentanoic acid (CAS 1485492-68-9)
- 2-((5-(2-Hydroxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(naphthalen-2-yl)-N-phenylacetamide (CAS 332908-90-4)
- Fmoc-4-Abz-OH (CAS 185116-43-2)
- N-(4-Bromo-2-methylphenyl)-5-oxoprolinamide (CAS 1048971-80-7)
- (3-Ethoxycarbonyl-5-nitrophenyl)boronic acid (CAS 850568-37-5)
- Agomelatine Impurity 11 (CAS 138113-07-2)
- 5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride (CAS 1241674-97-4)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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