Papaverine impurity 25 CAS 33520-96-6
| CAS No. | 33520-96-6 |
| Molecular Formula | C20H21NO5 |
| Molecular Weight | 355.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Papaverine impurity 25 (CAS 33520-96-6), a pharmacopoeial impurity reference standard (molecular formula C20H21NO5, MW 355.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H21NO5, Papaverine impurity 25 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 355.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H21NO5 |
| Molecular Weight | 355.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Papaverine Standards
- Papaverine EP Impurity B (Papaverinol) (CAS 482-76-8)
- Papaverine EP Impurity D (Papaveraldine) (CAS 522-57-6)
- Papaverine EP Impurity F (CAS 139-76-4)
- Papaverine impurity 24 (CAS 33490-73-2)
- Papaverine Impurity 26 (CAS CATO-C4X-206726)
- Papaverine Impurity 39 (CAS 75608-42-3)
- Papaverine Impurity 40 (CAS 361389-65-3)
- Papaverine Impurity 42 (CAS CATO-C4X-206742)
Recommended Standards
- Berberine Impurity 33 (CAS 100101-07-3)
- Indobufen Impurity 44 (CAS CATO-C4X-179244)
- Tranilast Impurity 11 (CAS CATO-C4X-252911)
- Ketorolac Impurity 37 (CAS CATO-C4X-166937)
- Cefixime Impurity 39 (CAS CATO-C4X-113939)
- Olaparib Impurity 125 (CAS CATO-C4X-1135125)
- SM7280A Impurity 3 (CAS CATO-C4X-32963)
- Methyl 1-Methyl-5-indolecarboxylate (CAS 128742-76-7)
- 4-Phenyl-2,3,8-triazaspiro[4.5]dec-3-en-1-one (CAS 473909-21-6)
- 5-(4-(Dimethylamino)phenyl)-1,3,4-oxadiazol-2-amine (CAS 59940-26-0)
- 1-Benzyl-4-(4-chlorophenyl)piperidin-4-ol (CAS 56108-25-9)
- Methyl 2-(3,4-dihydro-2H-pyrrol-5-yl)hydrazine-1-carboxylate (CAS 1306753-54-7)
- 1,3-Difluoro-2-ethoxy-4-nitrobenzene (CAS 1803828-86-5)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com