Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate CAS 335407-12-0
| CAS No. | 335407-12-0 |
| Molecular Formula | C23H20Cl2N2O4S |
| Molecular Weight | 491.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 491.39 g/mol gives Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-12-0), molecular formula C23H20Cl2N2O4S and molecular weight 491.39 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (C23H20Cl2N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H20Cl2N2O4S |
| Molecular Weight | 491.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Ethyl 4-{[2-(3,4-dichlorobenzamido)phenyl]sulfanyl}-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 439111-37-2)
- Ethyl 4-[3-(2,3-dichlorobenzamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-26-8)
- Ethyl 4-[3-(3,4-dichlorobenzamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-06-4)
- Methyl 2-(3,4-dichlorobenzamido)-4-methyl-5-(m-tolylcarbamoyl)thiophene-3-carboxylate (CAS 335409-72-8)
- Methyl 2-(2,4-dichlorobenzamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505095-81-8)
- Methyl 2-(2,4-dichlorobenzamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505095-97-6)
- (S)-2-(2,6-Dichlorobenzamido)-3-(2,6-dimethoxy-[1,1-biphenyl]-4-yl)propanoic acid (CAS 232271-19-1)
- Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-57-3)
Recommended Standards
- 2-((N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)-4-methoxyphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 400085-62-3)
- N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)methoxy)quinazolin-4-amine (CAS 781613-23-8)
- Tenofovir Impurity 28 (CAS 1246812-43-0)
- 9-[1,4]Benzoxaborino[2,3,4-kl]phenoxaborin-7-yl-1,3,6,8-tetramethyl-9H-carbazole (CAS 2170468-48-9)
- 2-(4-Methylbenzoyl)hydrazine-1-carbothioamide (CAS 1079-82-9)
- tert-Butyl 2-oxo-6-azaspiro[3.5]nonane-6-carboxylate (CAS 1359704-84-9)
- 3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Pentadecafluorononan-2-one (CAS 754-85-8)
- 2-Chloro-N-(3-(pyrazin-2-yloxy)phenyl)acetamide (CAS 866157-08-6)
- 2-(2-(4-Chlorophenyl)-7-methyl-5-oxoimidazo[1,2-a]pyrimidin-8(5H)-yl)acetic acid (CAS 902836-44-6)
- 1,1,1-trifluoro-3,3-dimethylbutan-2-one (CAS 359-61-5)
- 5-Iodo-6-nitroquinoline (CAS 618397-63-0)
- (-)-asarinin (CAS 133-04-0)
- 2-((2,4-Dichlorophenyl)amino)thiazole-4-carboxylic acid (CAS 728918-54-5)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
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