Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate CAS 335407-57-3
| CAS No. | 335407-57-3 |
| Molecular Formula | C21H24Cl2N2O4S |
| Molecular Weight | 471.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-57-3) is a high-purity analytical reference standard with the molecular formula C21H24Cl2N2O4S and a molecular weight of 471.40 g/mol.
Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (C21H24Cl2N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H24Cl2N2O4S |
| Molecular Weight | 471.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- (S)-2-(2,6-Dichlorobenzamido)-3-(2,6-dimethoxy-[1,1-biphenyl]-4-yl)propanoic acid (CAS 232271-19-1)
- Methyl 2-(3,4-dichlorobenzamido)-4-methyl-5-(m-tolylcarbamoyl)thiophene-3-carboxylate (CAS 335409-72-8)
- Ethyl 4-[3-(2,3-dichlorobenzamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-26-8)
- Ethyl 4-[3-(3,4-dichlorobenzamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-06-4)
- 4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid (CAS 107097-80-3)
- Methyl 2-(3,4-dichlorobenzamido)-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate (CAS 335406-47-8)
- Methyl 2-(2,4-dichlorobenzamido)-5-((3,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-12-0)
- Ethyl 4-{[2-(3,4-dichlorobenzamido)phenyl]sulfanyl}-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 439111-37-2)
Recommended Standards
- 6,8-Dichloro-3-(2,6-dimethylphenyl)-2-(((4-methoxyphenyl)thio)methyl)quinazolin-4(3H)-one (CAS 338957-61-2)
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