2-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one CAS 336119-88-1
| CAS No. | 336119-88-1 |
| Molecular Formula | C19H20ClN3O |
| Molecular Weight | 341.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 341.83 g/mol gives 2-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one (CAS 336119-88-1), a certified reference material (molecular formula C19H20ClN3O, MW 341.83 g/mol) for analytical method development and quality control.
The molecular framework of 2-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one (C19H20ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20ClN3O |
| Molecular Weight | 341.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- (E)-1-(4-(2-amino-4-chlorophenyl)piperazin-1-yl)-3-phenylprop-2-en-1-one (CAS 879590-27-9)
- (R)-2-(1-amino-2-methylpropyl)-3-benzyl-7-chloro-4H-chromen-4-one (CAS 618430-69-6)
- 2-((4-(2-Amino-2-oxoethyl)thiazol-2-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 954019-33-1)
- 5-Amino-4-(benzo[d]thiazol-2-yl)-1-(4-chlorophenyl)-1,3-dihydro-2h-pyrrol-2-one (CAS 885458-21-9)
- 5-Amino-4-benzothiazol-2-yl-1-(4-chloro-phenyl)-1,2-dihydro-pyrrol-3-one (CAS 457638-88-9)
- 5-Amino-1-(2-chlorobenzyl)-N-(m-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899981-44-3)
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Recommended Standards
- 1'-Benzyl-6-chlorospiro[chroman-2,4'-piperidin]-4-one (CAS 81122-68-1)
- 2,2,2-Trichloro-N-(2,4,5-trichlorophenyl)acetamide (CAS 33560-57-5)
- 1-[(4-Chlorophenyl)methyl]-3-methyl-4-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860785-29-1)
- 3-Chloro-N-(2-methyl-1-(6-methyl-1H-benzo[d]imidazol-2-yl)propyl)benzamide (CAS 338422-99-4)
- 2-amino-5-bromopyridin-4-ol (CAS 1261269-33-3)
- 1H-Pyrazole-4-carboxylic acid, 1,5-diphenyl-, ethyl ester 53561-07-2 CTK1G0668 (CAS 53561-07-2)
- 2-(2-Bromophenyl)pyrimidine-5-carboxylic acid (CAS 1315364-07-8)
- 6-Chloro-3-phenylpyridazin-4-amine (CAS 79852-16-7)
- Methyl (2R,4R)-1-Boc-4-aminopyrrolidine-2-carboxylate (CAS 1146160-08-8)
- (2,1,3-Benzoxadiazol-5-yl)methanol (CAS 59660-56-9)
- 2-(((3-Methoxypyrazin-2-yl)methyl)amino)acetic acid (CAS 1353979-03-9)
- 7-bromo-5-chloro-3-methyl-1-benzofuran-2-carboxylic acid (CAS 1019111-85-3)
- 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 26771-69-7)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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