2-((5-(m-Tolyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide CAS 337490-49-0
| CAS No. | 337490-49-0 |
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-(m-Tolyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide.
2-((5-(m-Tolyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 337490-49-0) is a high-purity analytical reference standard with the molecular formula C18H14F3N3O2S and a molecular weight of 393.38 g/mol.
Based on its molecular formula C18H14F3N3O2S, 2-((5-(m-Tolyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 393.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((5-(m-Tolyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related m Standards
- 1,3-Bis[3-(4-tolyl)-1,2,4-oxadiazolyl]benzene (CAS 1965304-71-5)
- 1,3-Bis ((3-(2-tolyl)-1,2,4-oxadiazol)-5-yl)benzene (CAS 1965304-96-4)
- 1,3-Bis[3-(3-tolyl)-1,2,4-oxadiazolyl]benzene (CAS 1965304-98-6)
- 8-(P-tolyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine (CAS 691869-98-4)
- 3-(5-p-Tolyl-1H-pyrrol-2-yl)-propionic acid (CAS 329217-03-0)
- 1-(P-tolyl)-3-((3,4,4-trifluorobut-3-en-1-yl)thio)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 691868-96-9)
- 1-(p-Tolyl)-3-(3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyridazin-4(1H)-one (CAS 1115963-56-8)
- 3-[p-Tolyl-(3-trifluoromethyl-benzenesulfonyl)-amino]-propionic acid (CAS 571158-84-4)
Recommended Standards
- 2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 688335-38-8)
- N-(4-Phenoxyphenyl)-3-trifluoromethylbenzenesulfonamide (CAS 292867-24-4)
- 1-(4-(Difluoromethyl)-6-(3,4-dimethoxyphenyl)pyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 870260-43-8)
- Riociguat impurity 27 (CAS CATO-C4X-174927)
- methyl 2-(trifluoromethyl)-1,3-oxazole-5-carboxylate (CAS 1803603-75-9)
- 2-(p-Tolylamino)isonicotinonitrile (CAS 137225-07-1)
- 3-(4,5-Dihydro-4-phenyl-5-thioxo-1H-1,2,4-triazol-3-yl)-N,N-diethylbenzenesulfonamide (CAS 438021-60-4)
- 3-(2-methyl-2H-1,2,3-triazol-4-yl)propan-1-ol (CAS 1849290-27-2)
- 3-((1H-1,2,4-triazol-1-yl)methyl)-4-chloroaniline (CAS 1094675-62-3)
- 2,2-Bis(4-hydroxyphenyl)acetaldehyde (CAS 103707-82-0)
- (3,5-Dibromo-1H-1,2,4-triazol-1-yl)methanol (CAS 1674389-79-7)
- N-(1-Chloro-2-oxo-2-phenylethyl)benzamide (CAS 41260-69-9)
- 2-(1-(2-Chlorophenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1239700-56-1)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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