2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide CAS 337498-65-4
| CAS No. | 337498-65-4 |
| Molecular Formula | C18H16N4O5S |
| Molecular Weight | 400.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 400.41 g/mol gives 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide (CAS 337498-65-4), a certified reference material (molecular formula C18H16N4O5S, MW 400.41 g/mol) for analytical method development and quality control.
Structurally, 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide (C18H16N4O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 400.41 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16N4O5S |
| Molecular Weight | 400.41 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methoxyphenyl Standards
- 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-methyl-3-nitrophenyl)acetamide (CAS 337498-67-6)
- 4-[4-(4-Methoxyphenyl)pyrimidin-2-yl]phenyl 4-fluorobenzoate (CAS 477857-35-5)
- 3-(2-Methoxyphenyl)-4-((2,4,5-trimethoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-72-3)
- 3-(2-Methoxyphenyl)-4-((2,4,6-trimethoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478257-36-2)
- S-(2-((4-Methoxyphenyl)amino)-2-oxoethyl) carbamothioate (CAS 5429-06-1)
- N-(2-Methoxyphenyl)-6-((p-tolyloxy)methyl)-[1,2,4]triazolo[3,4-c][1,2,4,5]dithiadiazin-3-amine (CAS 127399-38-6)
- 3-(2-Methoxyphenyl)-5-methyl-7-(4-phenylpiperazin-1-yl)pyrazolo[1,5-a]pyrimidine (CAS 879584-20-0)
- 4-(4-Methoxyphenyl)-6-(4-methylpiperazin-1-yl)-2-(m-tolyl)pyrimidine-5-carbonitrile (CAS 477859-04-4)
Recommended Standards
- VU-6001376, >98% (HPLC) (CAS 1968546-34-0)
- N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers) (CAS 1190008-84-4)
- 3-(6-Nitrobenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 918154-69-5)
- 1,6-Anhydro-|A-D-glucopyranose 4-Diacetate 2-(4-Methylbenzenesulfonate) 3,4-Di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-|A-D-glucopyranose 84207-46-5 (CAS 84207-46-5)
- N-(3,5-dimethylphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 955966-52-6)
- Methyl (Z)-2-cyano-3-phenyl-but-2-enoate (CAS 14533-90-5)
- 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer with butyl 2-propenoate, ethenylbenzene and 2-propenoic acid (CAS 26985-11-5)
- 4-Benzyl-8-chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine (CAS 956431-23-5)
- 1-(2-Bromo-1-(sec-butoxy)ethyl)-2-fluorobenzene (CAS 1249380-68-4)
- 5-Cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 861408-98-2)
- tert-Butyl 4-{5-cyano-[2,3'-bipyridin]-6-yl}-1,4-diazepane-1-carboxylate (CAS 946385-97-3)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)sulfonyl)phenyl)boronic acid (CAS 1704073-79-9)
- 4-Ethyl-6-methyl-1,3,5-triazin-2-amine (CAS 17584-13-3)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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