3-Chloro-2-[4-(1-phenyl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]-5-(trifluoromethyl)pyridine CAS 337919-75-2
| CAS No. | 337919-75-2 |
| Molecular Formula | C19H17ClF3N5 |
| Molecular Weight | 407.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-2-[4-(1-phenyl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]-5-(trifluoromethyl)pyridine (C19H17ClF3N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-Chloro-2-[4-(1-phenyl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]-5-(trifluoromethyl)pyridine (CAS 337919-75-2), molecular formula C19H17ClF3N5 and molecular weight 407.82 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-2-[4-(1-phenyl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]-5-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H17ClF3N5 |
| Molecular Weight | 407.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- (3E)-2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-4-phenylbut-3-enenitrile (CAS 321432-67-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-isopropylphenyl)-1H-pyrrole-2-carboxamide (CAS 338956-40-4)
- 2-[(2E)-2-{[(2-chloro-4-fluorophenyl)methoxy]imino}ethyl]-9,10-dihydroanthracene-9,10-dione (CAS 338961-93-6)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338775-17-0)
- 2-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}sulfanyl)-4-[(E)-2-phenylethenyl]pyrimidine (CAS 338407-64-0)
- 2-[4-Chloro-3-(trifluoromethyl)benzenesulfonamido]-3-phenylpropanoic acid (CAS 1008052-19-4)
- N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[(4-methylphenyl)sulfonyl]glycine (CAS 592471-10-8)
- 2-Chloro-3-(4-(3-(furan-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)naphthalene-1,4-dione (CAS 1030603-63-4)
Recommended Standards
- 2-Amino-3-(4-chlorobenzoyl)-N-(2-fluorophenyl)indolizine-1-carboxamide (CAS 898437-02-0)
- 4-[(1E)-[(2,4-Difluorophenyl)imino]methyl]phenyl 4-chlorobenzene-1-sulfonate (CAS 331461-00-8)
- Ethyl 1-(4-(5-chlorothiophen-2-yl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956781-14-9)
- 2-(4-(4-Chlorophenyl)-1-oxophthalazin-2(1H)-yl)-N-(4-fluorophenyl)acetamide (CAS 684234-60-4)
- 1,3-Dihydrospiro[indene-2,2'-pyrrolidine]-5,6-diol (CAS 100038-08-2)
- Methyl 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononanoate (CAS 110260-75-8)
- (S)-2-amino-N-isopentyl-4-methylpentanamide (CAS 84851-37-6)
- 3-(4-Chlorobenzyl)tetrahydro-2h-pyran-3-amine (CAS 1339854-70-4)
- 3-chloropyrido[3,4-b]pyrazine (CAS 1774892-76-0)
- 4,5-Diaminobenzene-1,2-diol hydrobromide (CAS 511512-23-5)
- 2-((4-Bromobenzyl)oxy)-1,4-difluorobenzene (CAS 845866-76-4)
- 1-(3,3-dimethylbutyl)piperazin-2-one (CAS 1249798-09-1)
- Indole-2,4,5,6,7-d5-3-acetamide (CAS 1204700-53-7)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com