N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)ethyl)-N-methyl-2-phenylacetamide CAS 337919-77-4
| CAS No. | 337919-77-4 |
| Molecular Formula | C17H16ClF3N2O2 |
| Molecular Weight | 372.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)ethyl)-N-methyl-2-phenylacetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)ethyl)-N-methyl-2-phenylacetamide (CAS 337919-77-4) is a high-purity analytical reference standard with the molecular formula C17H16ClF3N2O2 and a molecular weight of 372.77 g/mol.
Structurally, N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)ethyl)-N-methyl-2-phenylacetamide (C17H16ClF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 372.77 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)ethyl)-N-methyl-2-phenylacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16ClF3N2O2 |
| Molecular Weight | 372.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[3-(propan-2-yloxy)phenyl]acetamide (CAS 685107-49-7)
- 2-Chloro-3-(2,4-dioxopentan-3-yl)-1,4-dihydroxyanthracene-9,10-dione (CAS 89607-90-9)
- 3-chloro-4-methyl-2-oxo-2H-chromen-7-yl 3,3-dimethylbutan-2-yl methylphosphonate (CAS 875577-99-4)
- 4-((5-Chloro-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)oxy)-3-methoxybenzoic acid (CAS 881463-44-1)
- 4-Chloro-N-(3-(4-fluorobenzyl)-4-hydroxy-2-oxopyridin-1(2H)-yl)benzamide (CAS 477846-11-0)
- N-(3-Chloro-4-methoxyphenyl)-3-nitro-4-(1H-pyrazol-1-yl)benzamide (CAS 321570-91-6)
- Methyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfonyl}-3-(dimethylamino)prop-2-enoate (CAS 1823194-70-2)
- 7-Chloro-N-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2H-1,4-benzothiazine-4-carboxamide (CAS 338777-90-5)
Recommended Standards
- PF-6274484 (CAS 1035638-91-5)
- 2-(4-Chlorophenyl)-5-phenyl-3-(trifluoromethyl)benzofuran (CAS 821770-02-9)
- 1-(4-Chlorobenzyl)-3-phenyl-1-(3,3,3-trifluoro-2-hydroxypropyl)urea (CAS 478258-83-2)
- Roxadustat Glycine (CAS 808116-60-1)
- H-Pro-His-Val-OH (H-4760.0100) (CAS 83960-33-2)
- 2-Chloro-4-(5-methyl-1,2,4-oxadiazol-3-yl)pyridine (CAS 1823915-67-8)
- 2-Amino-5-chloro-3-methylbenzamide (CAS 1006619-83-5)
- 2-Fluoro-N-(thiazol-5-ylmethyl)aniline (CAS 1341402-11-6)
- 2-(2-Methyl-3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)propanoic acid (CAS 876717-57-6)
- 3-Isothiocyanato-1-(2-methyl-benzyl)-1h-pyrazole (CAS 1004193-32-1)
- 2-{3,5-dioxo-10-oxa-4-azatricyclo[5.2.1.0,2,6]decan-4-yl}propanoic acid (CAS 154902-09-7)
- 2-((4-Chlorobenzyl)thio)-6-((methylthio)methyl)pyrimidin-4(3H)-one (CAS 860649-60-1)
- 3-[(2-chloroacetamido)methyl]-N-cyclopropylbenzamide (CAS 1311317-71-1)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
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