2-{2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}-1,3-benzothiazole CAS 337920-49-7
| CAS No. | 337920-49-7 |
| Molecular Formula | C18H11ClN2S2 |
| Molecular Weight | 354.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}-1,3-benzothiazole.
2-{2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}-1,3-benzothiazole (CAS 337920-49-7) is a high-purity analytical reference standard with the molecular formula C18H11ClN2S2 and a molecular weight of 354.88 g/mol.
2-{2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}-1,3-benzothiazole (C18H11ClN2S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-{2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}-1,3-benzothiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11ClN2S2 |
| Molecular Weight | 354.88 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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