Desloratadine impurity 66 CAS CATO-C4X-143066
| CAS No. | CATO-C4X-143066 |
| Molecular Formula | C21H23ClN2O |
| Molecular Weight | 354.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Desloratadine impurity 66 (CAS CATO-C4X-143066), a pharmacopoeial impurity reference standard (molecular formula C21H23ClN2O, MW 354.87 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Desloratadine impurity 66 (C21H23ClN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Desloratadine impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23ClN2O |
| Molecular Weight | 354.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Desloratadine Standards
- Desloratadine Impurity 28 (CAS CATO-C4X-143028)
- Desloratadine Related Compound A (CAS 117796-50-6)
- Desloratadine Impurity 64 (CAS CATO-C4X-143064)
- Desloratadine Impurity 65 (CAS CATO-C4X-143065)
- Desloratadine Impurity 9 (CAS 117796-52-8)
- Desloratadine Impurity 63 (CAS CATO-C4X-143063)
- Desloratadine Impurity 29 (CAS 79779-58-1)
- Iso Desloratadine Hydrochloride (CAS 432543-89-0)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com