Dimethyl 5-(3-chlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide CAS 337920-85-1
| CAS No. | 337920-85-1 |
| Molecular Formula | C16H14ClNO5S |
| Molecular Weight | 367.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dimethyl 5-(3-chlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide.
Dimethyl 5-(3-chlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide (CAS 337920-85-1), molecular formula C16H14ClNO5S and molecular weight 367.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Dimethyl 5-(3-chlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide (C16H14ClNO5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Dimethyl 5-(3-chlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClNO5S |
| Molecular Weight | 367.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dimethyl Standards
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Recommended Standards
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- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 298215-04-0)
- 4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate (CAS 331460-60-7)
- (E)-1-(3-Furanyl)-3-phenyl-2-propen-1-one (CAS 160560-19-0)
- 1-(2-(Diethylamino)-2-oxoethyl)piperidine-4-carboxylic acid (CAS 1156269-83-8)
- Methyl p-Tolyl Sulfone (CAS 3185-99-7)
- 4-ethylpiperidin-4-ol (CAS 550369-44-3)
- rel-(1R,5S,6s)-3-methyl-3-azabicyclo[3.1.0]hexane-6-carboxylic acid;hydrochloride (CAS 2170530-54-6)
- N-(Undec-10-en-1-yl)pent-4-ynamide (CAS 920279-10-3)
- 2,2-Dioctylpropane-1,3-diol (CAS 106868-09-1)
- 4-(Naphthalen-2-yl)pyrimidine-2-thiol (CAS 832740-99-5)
- (Z)-3-(hydroxyimino)-1-phenylquinoline-2,4(1H,3H)-dione (CAS 36412-08-5)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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