(2Z)-2-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-2,3-dihydro-1H-inden-1-one CAS 337921-23-0
| CAS No. | 337921-23-0 |
| Molecular Formula | C22H16ClNO |
| Molecular Weight | 345.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z)-2-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-2,3-dihydro-1H-inden-1-one.
CATO supplies (2Z)-2-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 337921-23-0), a certified reference material (molecular formula C22H16ClNO, MW 345.82 g/mol) for analytical method development and quality control.
Structurally, (2Z)-2-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-2,3-dihydro-1H-inden-1-one (C22H16ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 345.82 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2Z)-2-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-2,3-dihydro-1H-inden-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16ClNO |
| Molecular Weight | 345.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (2E)-N-(5-Chloro-2-methoxyphenyl)-3-(4-propoxyphenyl)prop-2-enamide (CAS 803741-19-7)
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- 3-(N-Ethyl4-chlorobenzenesulfonamido)thiophene-2-carboxylic acid (CAS 1707392-13-9)
- (4-(4-Aminophenyl)piperazin-1-yl)(5-chloro-2-methoxyphenyl)methanone (CAS 892693-46-8)
- 2-(Allylamino)-N-benzylbenzamide (CAS 1408002-67-4)
- n-(2-(Pyridin-3-yl)ethyl)benzamide (CAS 107776-87-4)
- 2-Fluoro-4-(trifluoromethyl)nicotinaldehyde (CAS 1227599-63-4)
- 3-methyl-6-(pyrimidin-4-yl)-2-sulfanyl-3,4-dihydropyrimidin-4-one (CAS 503860-53-5)
- 5-(Methoxymethyl)pyridine-3-boronic acid pinacol ester (CAS 1174766-05-2)
- Ethyl 2-(3,5-difluoro-4-iodophenyl)acetate (CAS 2385942-02-7)
- 1-(2'-Fluoro-[1,1'-biphenyl]-4-yl)propan-1-ol (CAS 64820-95-7)
- spiro[bicyclo[2.2.1]heptane-2,2’-morpholine] (CAS 1559914-99-6)
- Relugolix Impurity 165 (CAS CATO-C4X-2429165)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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