1-[(4-Chlorophenyl)methyl]-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one CAS 338783-47-4
| CAS No. | 338783-47-4 |
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-[(4-Chlorophenyl)methyl]-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one (CAS 338783-47-4) is a high-purity analytical reference standard with the molecular formula C18H20ClN3O2 and a molecular weight of 345.82 g/mol.
The molecular framework of 1-[(4-Chlorophenyl)methyl]-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one (C18H20ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-[(4-Chlorophenyl)methyl]-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
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Recommended Standards
- 1-[(2H-1,3-Benzodioxol-5-yl)methyl]-4-[(6-chloropyridin-3-yl)methyl]piperazine (CAS 861211-55-4)
- 1-Benzyl-3-chloro-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one (CAS 339024-49-6)
- 1-(3-Chlorobenzyl)-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one (CAS 338754-96-4)
- 1-Chloro-3-methyl-2-(4-methylbenzyl)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 862106-12-5)
- 1-(4,6-Dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl)-3-phenylthiourea (CAS 131944-98-4)
- Tert-butyl 8-nitro-4-oxospiro[chromane-2,4'-piperidine]-1'-carboxylate (CAS 1415819-76-9)
- (Z)-3-Methyl-4-(4-nitrobenzylidene)isoxazol-5(4H)-one (CAS 61588-02-1)
- 1-Phenyl-3,5-bis(trifluoromethyl)-1H-pyrazole (CAS 140647-19-4)
- 5,6-Dichloro-2-methoxynicotinaldehyde (CAS 2248640-92-6)
- [2-(4-Fluorophenyl)ethyl][(2-methoxy-1,3-thiazol-5-yl)methyl]amine hydrochloride (CAS 1332531-07-3)
- 4-(Difluoromethoxy)-2-iodo-1-methylbenzene (CAS 1261453-69-3)
- (5-(Benzyloxy)pyridin-2-yl)methanamine (CAS 849807-17-6)
- 2-(Propylthio)nicotinamide (CAS 175135-26-9)
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