Ethyl 2-{3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]pyridin-2-yl}acetate CAS 338392-15-7
| CAS No. | 338392-15-7 |
| Molecular Formula | C22H17ClF3N3O4 |
| Molecular Weight | 479.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-{3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]pyridin-2-yl}acetate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 2-{3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]pyridin-2-yl}acetate (CAS 338392-15-7), a certified reference material (molecular formula C22H17ClF3N3O4, MW 479.84 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Ethyl 2-{3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]pyridin-2-yl}acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 479.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17ClF3N3O4 |
| Molecular Weight | 479.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 3-Chloro-2-(3-(1-(phenylsulfonyl)-1H-pyrazol-3-yl)phenoxy)-5-(trifluoromethyl)pyridine (CAS 321385-86-8)
- N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyridin-3-yl)-4-fluorobenzamide (CAS 478262-13-4)
- 2-((4-Chloro-N-(2,4-dichloro-5-isopropoxyphenyl)phenyl)sulfonamido)-N,N-dimethylacetamide (CAS 338967-44-5)
- 3-[2-Chloro-4-(4-chlorophenoxy)phenyl]-1-(4-chlorobenzenesulfonyl)-1H-pyrazole (CAS 321522-28-5)
- 4-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-yl}-6-hydroxy-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrimidin-2-one (CAS 866051-56-1)
- N-[(4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl)carbonyl]-N'-[3,5-di(trifluoromethyl)phenyl]urea (CAS 650615-81-9)
- 1-(5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)thiophen-2-yl)-2-(quinoxalin-2-ylthio)ethan-1-one (CAS 339016-49-8)
- N-(3-chloro-2-methylphenyl)-2-((3-(furan-2-ylmethyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 902938-07-2)
Recommended Standards
- (E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one (CAS 865659-46-7)
- N-tetradecylstearamide (CAS 146177-66-4)
- 5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxamide (CAS 321553-23-5)
- N-nitroso-desmethyl-demeclocycline (CAS CATO-C4X-160811)
- 2-Chloro-4-cyclopropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1824315-26-5)
- (R)-methyl 5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate (CAS 929095-51-2)
- 5-(3,4-Difluorophenyl)nicotinic acid (CAS 1048486-16-3)
- 6-Bromobenzo[b]thiophene-3-carbaldehyde (CAS 19075-53-7)
- Cereulide (CAS 157232-64-9)
- 3-Bromo-5-(1,1-difluoropropyl)pyridine (CAS 2792167-40-7)
- 3-Methyl-1-(phenylsulfanyl)butan-2-one (CAS 71221-49-3)
- 4-Amino-2,3,3-trimethylisothiazolidine 1,1-dioxide (CAS 2138271-48-2)
- 1-Benzyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1185287-60-8)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com