(E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one CAS 865659-46-7
| CAS No. | 865659-46-7 |
| Molecular Formula | C21H17ClF3N5O3 |
| Molecular Weight | 479.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one (CAS 865659-46-7) is a high-purity analytical reference standard with the molecular formula C21H17ClF3N5O3 and a molecular weight of 479.84 g/mol.
The molecular framework of (E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one (C21H17ClF3N5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures (E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17ClF3N5O3 |
| Molecular Weight | 479.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related E Standards
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- 2-(1H-benzo[d][1,2,3]triazol-1-yl)-2-(9H-carbazol-9-yl)-1,1-diphenylethan-1-ol (CAS 132724-62-0)
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- 3-(N-(Benzo[d][1,3]dioxol-5-yl)sulfamoyl)-N-(2-(2-methyl-1H-benzo[d]imidazol-1-yl)ethyl)benzamide (CAS 920882-44-6)
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Recommended Standards
- 5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxamide (CAS 321553-23-5)
- Ethyl 2-{3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]pyridin-2-yl}acetate (CAS 338392-15-7)
- N-nitroso-desmethyl-demeclocycline (CAS CATO-C4X-160811)
- N-tetradecylstearamide (CAS 146177-66-4)
- 2-(((3-Acetylphenyl)imino)methyl)-3-hydroxy-1H-inden-1-one (CAS 1023482-45-2)
- tert-Butyl 4-phenoxypiperidine-1-carboxylate (CAS 155989-69-8)
- (2-Chloro-4-fluoropyridin-3-yl)methanol (CAS 1805639-41-1)
- Gemcitabine Impurity 26 (CAS 122111-12-0)
- 5-Butyl-3-ethyl-6-methylpyrimidine-2,4(1H,3H)-dione (CAS 91216-49-8)
- 6-methoxyquinoline-2-carbaldehyde (CAS 89060-22-0)
- 1-{2-[2-(6-Chloro-pyridazin-3-yl)-ethyl]-pyrrolidin-1-yl}-ethanone (CAS 1316218-48-0)
- N-(2-Ethylphenyl)-5-methylfuran-2-carboxamide (CAS 544679-85-8)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(2,3-dimethoxybenzyl)propanoic acid (CAS 1260605-04-6)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com