3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide CAS 338395-75-8
| CAS No. | 338395-75-8 |
| Molecular Formula | C20H16ClF3N4O3 |
| Molecular Weight | 452.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide.
3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide (CAS 338395-75-8), molecular formula C20H16ClF3N4O3 and molecular weight 452.81 g/mol, is a CATO reference standard with documented purity and traceability.
3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide (C20H16ClF3N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16ClF3N4O3 |
| Molecular Weight | 452.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
- 5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 609793-43-3)
- 4-(4-Chlorophenyl)-3-(4-methoxyphenyl)-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazole (CAS 618880-63-0)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 477329-11-6)
- 1-Benzyl-3-[(4-chlorophenyl)sulfanyl]-4-[(4-methoxyphenyl)amino]pyrrolidine-2,5-dione (CAS 317821-86-6)
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-7-(4-methoxyphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1226448-86-7)
- 2-(4-(2-Chlorophenyl)piperazin-1-yl)-7-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226458-51-0)
- 7-(2-Chlorophenyl)-2-(4-(2-methoxyphenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1242932-94-0)
- 3-(4-Chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one (CAS 586988-78-5)
Recommended Standards
- 3-Bromo-2,6-diiodobenzoic acid (CAS 1797415-91-8)
- 4-Bromo-3,5-diiodobenzoic acid (CAS 861117-99-9)
- 4-Bromo-2,6-diiodobenzoic acid (CAS 1797415-88-3)
- 5-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-chloro-3-iodopyridine (CAS 1203499-04-0)
- 1-(3,4-Dimethylbenzyl)-1H-pyrrole-3-carboxylic acid (CAS 1500889-67-7)
- 3-((2,4-Dimethylphenyl)carbamoyl)naphthalen-2-yl acetate (CAS 4569-00-0)
- 1-(3,5-Dichloropyridin-2-yl)-1h-pyrazol-4-amine (CAS 1247532-79-1)
- N-[3-(3-Amino-4-nitrophenoxy)phenyl]-3-(trifluoromethyl)benzene-1-sulfonamide (CAS 1400989-38-9)
- tert-butyl 6-azido-6-benzyl-2-azaspiro[3.3]heptane-2-carboxylate (CAS 2751687-57-5)
- N'-Hydroxy-2-[(4-methylphenyl)sulfonyl]-ethanimidamide (CAS 72660-98-1)
- 4-(Thiophen-2-yl)piperidine-4-carboxylic acid (CAS 787524-72-5)
- 3-(4,5-Dihydro-1H-imidazol-2-yl)-1-methyl-1H-indazole (CAS 1649964-41-9)
- (1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]Heptan-2-amine (CAS 32511-35-6)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
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