5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 609793-43-3
| CAS No. | 609793-43-3 |
| Molecular Formula | C24H18ClFN2O4 |
| Molecular Weight | 452.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 609793-43-3), molecular formula C24H18ClFN2O4 and molecular weight 452.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (C24H18ClFN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H18ClFN2O4 |
| Molecular Weight | 452.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 3-(2-Chlorophenyl)-5-methyl-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}-1,2-oxazole-4-carbohydrazide (CAS 338395-75-8)
- 4-(4-Chlorophenyl)-3-(4-methoxyphenyl)-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazole (CAS 618880-63-0)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 477329-11-6)
- 1-Benzyl-3-[(4-chlorophenyl)sulfanyl]-4-[(4-methoxyphenyl)amino]pyrrolidine-2,5-dione (CAS 317821-86-6)
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-7-(4-methoxyphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1226448-86-7)
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- 7-(2-Chlorophenyl)-2-(4-(2-methoxyphenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1242932-94-0)
- 3-(4-Chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one (CAS 586988-78-5)
Recommended Standards
- Methyl 7-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazine-3-carboxylate (CAS 318247-37-9)
- 5-Chloro-4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2771080-69-2)
- Hentriacontan-1-ol (CAS 544-86-5)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-2-(p-tolylthio)nicotinohydrazide (CAS 1024403-13-1)
- 3-Bromo-6-methylpicolinaldehyde (CAS 1060810-14-1)
- 4-(Difluoromethoxy)-2-methylbenzo[d]oxazole (CAS 1806325-53-0)
- 4-Methyl-2-(thiophen-2-yl)-1,3-thiazole-5-carboxamide (CAS 1097815-09-2)
- 3-Methoxyazetidine-1-sulfonamide (CAS 1427081-07-9)
- 4-(Benzo[d][1,3]dioxole-5-carbonyl)piperazin-2-one (CAS 1030820-72-4)
- N-(4-Ethylphenyl)-2,3,5,6-tetrafluorobenzenamine (CAS 332903-60-3)
- 1-(Cyclopropylmethyl)-1H-imidazol-4-amine (CAS 1260879-14-8)
- 3-Allyl-4-ethoxybenzaldehyde (CAS 915922-34-8)
- 3-Ethoxy-N-(2-fluorobenzyl)aniline (CAS 1040685-59-3)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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