4-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate CAS 338396-26-2
| CAS No. | 338396-26-2 |
| Molecular Formula | C16H14ClF3N2O4S |
| Molecular Weight | 422.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (C16H14ClF3N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-26-2), a certified reference material (molecular formula C16H14ClF3N2O4S, MW 422.81 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14ClF3N2O4S |
| Molecular Weight | 422.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonyl)morpholine (CAS 344277-88-9)
- 4-Chloro-2-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338406-02-3)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(1H-indol-3-yl)ethan-1-one (CAS 874671-31-5)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1H-indol-3-yl)pyrrolidine-2,5-dione (CAS 338962-80-4)
- 3-{[2-chloro-6-(1H-imidazol-1-yl)phenyl]methyl}-1-[3-(trifluoromethyl)benzoyl]urea (CAS 866042-66-2)
- 4-Chloro-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-nitrobenzene-1-sulfonamide (CAS 301314-58-9)
- 3-Chloro-2-({4-[(4-nitrophenyl)methoxy]phenyl}methyl)-5-(trifluoromethyl)pyridine (CAS 338402-10-1)
- 4-({3-[(2-chloro-6-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}methyl)benzene-1-sulfonamide (CAS 477869-78-6)
Recommended Standards
- 2-(4-Chlorophenyl)-6-[3-(trifluoromethyl)phenyl]-5H,6H,7H,7aH-pyrrolo[3,4-e][1,3]thiazine-5,7-dione (CAS 337920-06-6)
- N-Triacontane (CAS 638-68-6)
- 3-[Tris(trimethylsilyloxy)silyl]propyl Methacrylate (CAS 17096-07-0)
- Squalane (CAS 111-01-3)
- 3-(2-Methoxy-4-(trifluoromethoxy)phenyl)acrylic acid (CAS 1262019-21-5)
- (2-(Cyclopentyloxy)-3-methoxyphenyl)methanamine (CAS 1145680-28-9)
- 2-(Pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 933986-97-1)
- N-(3,5-Difluorobenzyl)-1-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1856083-76-5)
- N-(2-Chlorophenyl)-2-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-3-yl)acetamide (CAS 897464-44-7)
- 1-(2-Methoxybenzyl)guanidine (CAS 224947-74-4)
- 2-Amino-N-(2-(dimethylamino)ethyl)-4-methoxypyrimidine-5-carboxamide (CAS 84332-07-0)
- 2-Bromo-6-nitronaphthalene (CAS 67878-77-7)
- 5-Oxopyrrolidin-3-yl naphthalen-1-ylcarbamate (CAS 88015-98-9)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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