1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1H-indol-3-yl)pyrrolidine-2,5-dione CAS 338962-80-4
| CAS No. | 338962-80-4 |
| Molecular Formula | C19H14ClF3N4O2 |
| Molecular Weight | 422.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1H-indol-3-yl)pyrrolidine-2,5-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 422.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1H-indol-3-yl)pyrrolidine-2,5-dione (CAS 338962-80-4), a certified reference material (molecular formula C19H14ClF3N4O2, MW 422.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1H-indol-3-yl)pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14ClF3N4O2 |
| Molecular Weight | 422.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 3-{[2-chloro-6-(1H-imidazol-1-yl)phenyl]methyl}-1-[3-(trifluoromethyl)benzoyl]urea (CAS 866042-66-2)
- 3-Chloro-2-({4-[(4-nitrophenyl)methoxy]phenyl}methyl)-5-(trifluoromethyl)pyridine (CAS 338402-10-1)
- 4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonyl)morpholine (CAS 344277-88-9)
- 4-{[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-26-2)
- 4-Chloro-2-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338406-02-3)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(1H-indol-3-yl)ethan-1-one (CAS 874671-31-5)
- 4-Chloro-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-nitrobenzene-1-sulfonamide (CAS 301314-58-9)
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Recommended Standards
- (E)-2-(4-chlorophenyl)-N-((methoxyimino)methyl)-2-(3-(trifluoromethyl)quinoxalin-2-yl)acetamide (CAS 338412-29-6)
- Bendamustine USP Related Compound I (CAS 87475-54-5)
- 2-(4-Chlorophenyl)-6-[3-(trifluoromethyl)phenyl]-5H,6H,7H,7aH-pyrrolo[3,4-e][1,3]thiazine-5,7-dione (CAS 337920-06-6)
- Opicapone impurity 32 (CAS CATO-C4X-240432)
- 6-(2-Chloro-4-fluorophenyl)-6-oxohexanoic acid (CAS 951889-44-4)
- tert-Butyl 4-(2-hydroxycyclohexyl)piperazine-1-carboxylate (CAS 1267481-31-1)
- 2-(3-(Pyrrolidin-1-ylsulfonyl)phenyl)isonicotinic acid (CAS 1261992-29-3)
- 3,5-Difluoro-4'-propyl-1,1'-biphenyl (CAS 137528-87-1)
- (3R,4R)-3-fluoropiperidin-4-ol (CAS 1931963-05-1)
- (R)-2-(Piperidin-3-yl)isoindolin-1-one (CAS 1786495-37-1)
- 4-tert-Butoxyaniline (CAS 57120-36-2)
- 6-chloro-3-methyl-quinazolin-4-one (CAS 16064-09-8)
- Methyl 2-(3-bromo-2-hydroxyphenyl)acetate (CAS 628331-74-8)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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