3-((4-Chlorobenzyl)thio)-5-(trifluoromethyl)picolinonitrile CAS 338396-81-9
| CAS No. | 338396-81-9 |
| Molecular Formula | C14H8ClF3N2S |
| Molecular Weight | 328.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-((4-Chlorobenzyl)thio)-5-(trifluoromethyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-((4-Chlorobenzyl)thio)-5-(trifluoromethyl)picolinonitrile (CAS 338396-81-9), molecular formula C14H8ClF3N2S and molecular weight 328.74 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-((4-Chlorobenzyl)thio)-5-(trifluoromethyl)picolinonitrile (C14H8ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 328.74 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF3N2S |
| Molecular Weight | 328.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
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- N-(2-Chlorobenzyl)-4-(4-fluorophenyl)-1H-pyrrole-2-carboxamide (CAS 1219902-57-4)
- (E)-2-((2-chlorobenzyl)thio)-5-styryl-1,3,4-oxadiazole (CAS 1164453-19-3)
- (2-(4-Chlorobenzyl)propane-1,3-diyl)diphosphonic acid (CAS 103486-14-2)
- 3-((4-Chlorobenzyl)thio)-6-methylpyridazine (CAS 5273-39-2)
- 2-(4-Chlorobenzyl)-4-(4-isopropylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-34-2)
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Recommended Standards
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478050-36-1)
- Diethyl 2-(2-(4-chlorophenyl)-2-oxoethyl)-2-hydroxymalonate (CAS 400086-35-3)
- 1-[4-chloro-3-(trifluoromethyl)benzenesulfonyl]piperazine (CAS 97630-13-2)
- N-[2-chloro-5-(trifluoromethyl)phenyl]-1,3-benzothiazol-2-amine (CAS 380346-66-7)
- (3S,6S)-3,6-Octanediol (CAS 136705-66-3)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-N-(3-methoxyphenyl)acetamide (CAS 736954-80-6)
- 3-(Dimethylamino)cyclopentan-1-ol (CAS 1500723-24-9)
- Ethyl 8-amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate (CAS 191024-17-6)
- 2-((4-Amino-2-chlorobenzyl)thio)ethyl pyrimidine-5-carboxylate (CAS 7149-61-3)
- (4,6-Dimethoxy-1,3,5-triazin-2-yl)boronic acid (CAS 675880-39-4)
- 3,6-dihydro-2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-Pyridinecarboxylic acid 1,1-dimethylethyl ester (CAS 1572398-20-9)
- 5-Chloro-2,3,3-trimethyl-3H-indole (CAS 25981-83-3)
- Methyl 2-(3-hydroxypyrrolidin-1-yl)-5-(trifluoromethyl)benzoate (CAS 1956386-28-9)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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