2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile CAS 338397-59-4
| CAS No. | 338397-59-4 |
| Molecular Formula | C18H13ClF3N3O |
| Molecular Weight | 379.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile.
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile (CAS 338397-59-4), molecular formula C18H13ClF3N3O and molecular weight 379.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile (C18H13ClF3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-methoxyphenyl)pentanedinitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClF3N3O |
| Molecular Weight | 379.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 2-Chloro-5-{[3-(trifluoromethyl)phenyl]sulfamoyl}benzoic acid (CAS 328028-29-1)
- 3-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonamido)benzoic acid (CAS 612041-76-6)
- 3-(n-(2-Chloro-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid (CAS 326182-69-8)
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Recommended Standards
- Haloxyfop-methyl-d4 (CAS CATO-CCHM706050)
- Zinc, [[α,α'-(o-phenylenedinitrilo)di-o-cresolato](2-)]- (CAS 21380-07-4)
- N2-(4-methylphenyl)-N4-[4-(trifluoromethyl)phenyl]-6-chloro-1,3,5-triazine-2,4-diamine (CAS 680215-23-0)
- 2,4-Dibromo-5-fluoroiodobenzene (CAS 1000578-13-1)
- 5-Bromo-7-fluoro-8-methylquinoline (CAS 2101945-67-7)
- 2-Ethoxy-2-methylpropionic Acid (CAS 15001-71-5)
- 4-Nitro-N-(4-(5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide (CAS 89560-50-9)
- Methyl 2-(benzo[d]thiazole-6-carboxamido)benzo[d]thiazole-6-carboxylate (CAS 888409-17-4)
- Cycloheptane-1,4-diol (CAS 100948-92-3)
- 4-(2-((4-Nitronaphthalen-1-yl)oxy)ethyl)morpholine (CAS 317806-88-5)
- 4-(3-Hydroxyphenyl)-1H-pyrrole-3-carboxylic acid (CAS 1330755-09-3)
- Sodium Selenite Pentahydrate (CAS 26970-82-1)
- [2-(1H-Indol-4-yl)ethyl]dimethylamine (CAS 84401-01-4)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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