5-Methyl-2-(pyridin-3-yl)thiazol-4-yl 3-(trifluoromethyl)benzoate CAS 338399-01-2
| CAS No. | 338399-01-2 |
| Molecular Formula | C17H11F3N2O2S |
| Molecular Weight | 364.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Methyl-2-(pyridin-3-yl)thiazol-4-yl 3-(trifluoromethyl)benzoate (CAS 338399-01-2) is a high-purity analytical reference standard with the molecular formula C17H11F3N2O2S and a molecular weight of 364.34 g/mol.
The molecular framework of 5-Methyl-2-(pyridin-3-yl)thiazol-4-yl 3-(trifluoromethyl)benzoate (C17H11F3N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Methyl-2-(pyridin-3-yl)thiazol-4-yl 3-(trifluoromethyl)benzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H11F3N2O2S |
| Molecular Weight | 364.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-Methyl-2-(pyridin-2-yl)-1,3-thiazol-4-yl 3-(trifluoromethyl)benzoate (CAS 338399-06-7)
- 5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate (CAS 477873-07-7)
- 7-(Pyridin-4-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 625376-68-3)
- N-(Pyridin-3-ylmethyl)-4-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)thiazole-2-carboxamide (CAS 1251696-25-9)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 2,3-dichlorobenzoate (CAS 338399-14-7)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 2,4-dichlorobenzoate (CAS 338399-04-5)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 3,4-dichlorobenzoate (CAS 338399-10-3)
- 5-Methyl-2-(pyridin-3-yl)-1,3-thiazol-4-yl 2,3-dichlorobenzoate (CAS 338409-18-0)
Recommended Standards
- 4-{[5-Phenyl-4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}benzoic acid (CAS 255833-41-1)
- 6-{1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one (CAS 955966-55-9)
- 3'-(3-(Trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 79962-59-7)
- 6-Methyl-5-(4-phenylthiazol-2-yl)-2-(trifluoromethyl)nicotinic acid (CAS 651004-85-2)
- 1-(2-Fluorophenyl)-3-((1-(p-tolyl)-1H-tetrazol-5-yl)methyl)urea (CAS 920484-66-8)
- 3,5-Dichloropyrazine-2-carboxylic Acid (CAS 312736-49-5)
- 1-(4-(4-Chlorophenyl)-1H-pyrrol-3-yl)ethanone (CAS 87388-55-4)
- 2,4-Dioxo-1,3-diazaspiro[4.5]decane-7-carboxylic acid (CAS 26629-10-7)
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- 3-(2-Chlorophenyl)-2-cyanopropionic Acid (CAS 14650-19-2)
- 6-Fluoropyrazolo[1,5-a]pyridin-5-amine (CAS 2763600-95-7)
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