5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate CAS 477873-07-7
| CAS No. | 477873-07-7 |
| Molecular Formula | C17H11F3N2O2S |
| Molecular Weight | 364.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate (CAS 477873-07-7), a certified reference material (molecular formula C17H11F3N2O2S, MW 364.34 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Methyl-2-(pyridin-4-yl)-1,3-thiazol-4-yl 4-(trifluoromethyl)benzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H11F3N2O2S |
| Molecular Weight | 364.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-Methyl-2-(pyridin-2-yl)-1,3-thiazol-4-yl 3-(trifluoromethyl)benzoate (CAS 338399-06-7)
- 5-Methyl-2-(pyridin-3-yl)thiazol-4-yl 3-(trifluoromethyl)benzoate (CAS 338399-01-2)
- 7-(Pyridin-4-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 625376-68-3)
- N-(Pyridin-3-ylmethyl)-4-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)thiazole-2-carboxamide (CAS 1251696-25-9)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 2,3-dichlorobenzoate (CAS 338399-14-7)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 2,4-dichlorobenzoate (CAS 338399-04-5)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-yl 3,4-dichlorobenzoate (CAS 338399-10-3)
- 5-Methyl-2-(pyridin-3-yl)-1,3-thiazol-4-yl 2,3-dichlorobenzoate (CAS 338409-18-0)
Recommended Standards
- 6-{1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one (CAS 955966-55-9)
- 6-Methyl-5-(4-phenylthiazol-2-yl)-2-(trifluoromethyl)nicotinic acid (CAS 651004-85-2)
- 4-{[5-Phenyl-4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}benzoic acid (CAS 255833-41-1)
- 8-Ethyl-3-(methoxymethoxy)naphthalen-1-yl trifluoromethanesulfonate (CAS 2621932-59-8)
- Ethyl 6-(Ethylamino)pyridazine-3-carboxylate (CAS 1823915-03-2)
- 4-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine (CAS 951233-66-2)
- 5-Amino-4-fluoro-2-methylbenzonitrile (CAS 1824053-65-7)
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- 3',5'-Dimethoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 1356826-17-9)
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