5-Acetyl-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)pyrimidine-2,4(1H,3H)-dione CAS 338399-19-2
| CAS No. | 338399-19-2 |
| Molecular Formula | C13H10ClF3N4O3 |
| Molecular Weight | 362.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Acetyl-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)pyrimidine-2,4(1H,3H)-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Acetyl-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)pyrimidine-2,4(1H,3H)-dione (CAS 338399-19-2) is a high-purity analytical reference standard with the molecular formula C13H10ClF3N4O3 and a molecular weight of 362.69 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-Acetyl-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)pyrimidine-2,4(1H,3H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 362.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Acetyl-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)pyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF3N4O3 |
| Molecular Weight | 362.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Acetyl Standards
- Methyl 2-chloro-5-(3-(difluoromethyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-4-fluorobenzoate (CAS 120890-11-1)
- Methyl 2-chloro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)benzoate (CAS 855316-19-7)
- Methyl 6-chloro-3-(2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)-2-methylbenzoate (CAS 355390-15-7)
- 3-Chloro-2-(5-(methylthio)-3-(trifluoromethyl)-1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 1823182-83-7)
- 5-Chloro-1-(tetrahydro-2H-pyran-2-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2072808-93-4)
- 3-(4-Chloro-3-isopropoxyphenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 133762-96-6)
- (4E)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[(dimethylamino)methylidene]-3-ethoxy-4,5-dihydro-1H-pyrazol-5-one (CAS 338420-92-1)
- 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-cyclopropyl-4,5-dihydroisoxazole-3-carboxamide (CAS 338399-52-3)
Recommended Standards
- 4,4-Dihexyl-4H-silolo[3,2-b:4,5-b']dithiophene (CAS 906372-08-5)
- Methyl (E)-3-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazono)-2-(1H-1,2,4-triazol-1-yl)propanoate (CAS 551930-85-9)
- 4-(6-(Bromomethyl)-2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)morpholine (CAS 1032758-45-4)
- N'1-(2-chloroacetyl)-2-{5-[3-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazol-2-yl}ethanohydrazide (CAS 680214-91-9)
- Methyl 3-amino-2-methyl-3-phenylpropanoate hydrochloride (CAS 1375471-75-2)
- 6-(Trifluoromethyl)-1h-1,3-benzodiazole-2-thiol (CAS 86604-73-1)
- trans-4-fluoropyrrolidin-3-amine;dihydrochloride (CAS 125197-40-2)
- 5-Chloro-6-methyl-3-(piperidin-1-yl)-1,2,4-triazine (CAS 1023814-54-1)
- (2-Methoxy-5-nitrophenyl)boronic acid (CAS 677746-35-9)
- 3-((tert-Butoxycarbonyl)amino)-3-(piperidin-2-yl)propanoicacid (CAS 886362-32-9)
- 5,8-Diazaspiro[3.5]nonan-7-one hydrochloride (CAS 1638768-29-2)
- 1-Bromo-4-(chloromethyl)-2,5-difluorobenzene (CAS 1341660-62-5)
- (Bicyclo[3.1.0]hexane-1,5-diyl)dimethanol (CAS 103478-23-5)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com