Methyl 6-chloro-3-(2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)-2-methylbenzoate CAS 355390-15-7
| CAS No. | 355390-15-7 |
| Molecular Formula | C14H10ClF3N2O4 |
| Molecular Weight | 362.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 6-chloro-3-(2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)-2-methylbenzoate (CAS 355390-15-7), molecular formula C14H10ClF3N2O4 and molecular weight 362.69 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 6-chloro-3-(2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)-2-methylbenzoate (C14H10ClF3N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 6-chloro-3-(2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)-2-methylbenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF3N2O4 |
| Molecular Weight | 362.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
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Recommended Standards
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- [1,2-Ethanediylbis[dimethylphosphine-κP]]methyl(4-methylphenyl)palladium (CAS 680621-10-7)
- Opicapone Impurity 10 (CAS CATO-C4X-240410)
- 2,3-Dibromo-5,6-difluorophenylacetonitrile (CAS 1806327-01-4)
- Stannous chloride (CAS 7772-99-8)
- Glucoaloe emodin (CAS 29010-56-8)
- 2-(2-((tert-Butoxycarbonyl)amino)pyridin-4-yl)acetic acid (CAS 887580-70-3)
- 2-Methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine (CAS 1540863-74-8)
- 4-Amino-N-(2-hydroxyethyl)-1-methyl-1H-pyrazole-5-carboxamide (CAS 1468846-49-2)
- 1-Cbz-2-methyl-piperidine-3-carboxylic acid (CAS 1871579-06-4)
- 4,6-Dimethyl-3-oxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-7-carboxylic acid (CAS 871884-74-1)
- 2,5-Dimethoxy-4-chlorophenethylamine Hydrochloride (CAS 88441-15-0)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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