2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-2-methylhydrazine-1-carboxamide CAS 338399-49-8
| CAS No. | 338399-49-8 |
| Molecular Formula | C14H11Cl2F3N4O |
| Molecular Weight | 379.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-2-methylhydrazine-1-carboxamide.
CATO supplies 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-2-methylhydrazine-1-carboxamide (CAS 338399-49-8), a certified reference material (molecular formula C14H11Cl2F3N4O, MW 379.16 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-2-methylhydrazine-1-carboxamide (C14H11Cl2F3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11Cl2F3N4O |
| Molecular Weight | 379.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-Chloro-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}ethyl)benzamide (CAS 1609408-52-7)
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- Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate (CAS 338978-88-4)
- 2-(2-Chloro-6-(4-chlorophenoxy)pyridin-4-yl)-5-ethyl-4-methylthiazole (CAS 266362-18-9)
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Recommended Standards
- (2Z)-2-[(Z)-3-Bromobenzoyl]-3-[(2,4-difluorophenyl)amino]-3-hydroxyprop-2-enenitrile (CAS 866151-83-9)
- 3-(4-Bromophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-70-8)
- 4-Amino-N-(4-iodo-5-methylisoxazol-3-yl)benzenesulfonamide (CAS 1024-37-9)
- 2-(4-Iodophenyl)-1-methyl-5-nitro-1H-benzo[d]imidazole (CAS 20648-13-9)
- {Methyl[(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)sulfonyl]amino}acetic acid (CAS 1119452-93-5)
- {5-[(dimethylamino)methyl]furan-2-yl}methanamine dihydrochloride (CAS 1803592-89-3)
- 2-(Oxazol-2-yl)ethanol (CAS 1211519-60-6)
- 8-chloro-4,6-dimethyl-5H,6H-benzo[c]2,7-naphthyridin-5-one (CAS 1551407-49-8)
- 2-{[(benzyloxy)carbonyl]amino}-2-cyclopropylacetic acid (CAS 159871-55-3)
- 1-(1-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-1-hydroxypropan-2-yl)-3-(m-tolyl)urea (CAS 1043908-01-5)
- 2-Cyclopropoxy-1,3-diethylbenzene (CAS 1243466-55-8)
- Methyl 4-methoxy-2-(2-methoxy-2-oxoethyl)benzoate (CAS 91497-75-5)
- 7-Chloro-6-fluoroisoquinolin-3-yl trifluoromethanesulfonate (CAS 2095607-17-1)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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