Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate CAS 338978-88-4
| CAS No. | 338978-88-4 |
| Molecular Formula | C18H16Cl2N2O3 |
| Molecular Weight | 379.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 379.24 g/mol gives Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate (CAS 338978-88-4), a certified reference material (molecular formula C18H16Cl2N2O3, MW 379.24 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate (C18H16Cl2N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzimidazol-1-yl]oxy}propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2N2O3 |
| Molecular Weight | 379.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
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- 1-Chloro-1-deoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside (CAS 64644-65-1)
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Recommended Standards
- Benodanil Impurity 2 (CAS 349110-20-9)
- N-(1-Cyanocyclohexyl)-2-(6,8-dichloro-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 878115-37-8)
- 4-Iodo-N-(2-thienylmethyl)benzenesulfonamide (CAS 339018-37-0)
- N-(4-iodo-2-isopropylphenyl)-2-methylbenzamide (CAS 434293-51-3)
- 3-fluoro-5-methoxy-pyridin-4-amine (CAS 1804379-42-7)
- Methyl 2-((2-((4-fluorophenyl)carbamoyl)thiophen-3-yl)sulfonyl)acetate (CAS 251097-21-9)
- 1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338408-92-7)
- 2-((4-Fluorobenzyl)oxy)-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)benzamide (CAS 1017370-54-5)
- 2-(Pyrimidin-4-ylamino)acetic acid (CAS 72971-95-0)
- 5-Chloro-4-methoxy-2-phenylpyrimidine (CAS 901311-79-3)
- Caspofungin Impurity 9 Acetate (CAS CATO-C4X-15759)
- 5-Chloro-4-methylthiophene-2-carboxylic acid (CAS 74598-03-1)
- N-(2-Chloroethyl)-1-imidazolesulfonamide (CAS 195051-72-0)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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