dimethyl 2-(2,4-dichlorophenoxy)malonate CAS 338400-10-5
| CAS No. | 338400-10-5 |
| Molecular Formula | C11H10Cl2O5 |
| Molecular Weight | 293.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 293.10 g/mol gives dimethyl 2-(2,4-dichlorophenoxy)malonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
dimethyl 2-(2,4-dichlorophenoxy)malonate (CAS 338400-10-5), molecular formula C11H10Cl2O5 and molecular weight 293.10 g/mol, is a CATO reference standard with documented purity and traceability.
dimethyl 2-(2,4-dichlorophenoxy)malonate (C11H10Cl2O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2O5 |
| Molecular Weight | 293.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- Tert-butyl 6-amino-6-(trifluoromethyl)-2-azaspiro[3.3]Heptane-2-carboxylate (CAS 2306275-08-9)
- 2-Chloromethyl-4-methyl-5-pentafluoroethylpyridine (CAS 1246466-49-8)
- 2-[(2S,4R)-4-methoxypyrrolidin-2-yl]-1H-imidazole dihydrochloride (CAS 1955474-39-1)
- Morpholine-2-carboximidamide (CAS 1519922-13-4)
- (4-(TRIFLUOROMETHYL)OXAZOL-5-YL)METHANOL (CAS 1824624-51-2)
- N-(4-(5-Bromothiophen-2-yl)thiazol-2-yl)-3-methoxybenzamide (CAS 391229-46-2)
- N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-2-((2-(3-methylpiperidin-1-yl)-2-oxoethyl)thio)acetamide (CAS 681224-96-4)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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