4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one CAS 338403-32-0
| CAS No. | 338403-32-0 |
| Molecular Formula | C12H10F3N3O2 |
| Molecular Weight | 285.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 338403-32-0), molecular formula C12H10F3N3O2 and molecular weight 285.22 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (C12H10F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 285.22 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O2 |
| Molecular Weight | 285.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Hydroxy Standards
- Ethyl 4-hydroxy-6-(trifluoromethyl)quinoline-2-carboxylate (CAS 1352935-29-5)
- N-Hydroxy-4-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzamide (CAS 1706457-30-8)
- 2-Ethyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-70-6)
- Ethyl 4-hydroxy-5-(trifluoromethyl)quinoline-3-carboxylate (CAS 56881-18-6)
- Ethyl 4-Hydroxy-6-(trifluoromethyl)quinoline-3-carboxylate (CAS 26893-12-9)
- Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 391-02-6)
- Ethyl 4-Hydroxy-8-(trifluoromethyl)-3-quinolinecarboxylate (CAS 23851-84-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(ethyl(methyl)amino)thiophen-2-yl)boronate (CAS 2223006-29-7)
Recommended Standards
- 3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-8-(trifluoromethyl)-, ethyl ester (CAS 31601-87-3)
- 5-Methyl-3-nitro-1-(3-(trifluoromethyl)benzyl)-1h-pyrazole (CAS 957400-33-8)
- 3-Methyl-4-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338394-40-4)
- 9-Trifluoromethyl-5,6,7,8-tetrahydro-pyrazolo-[5,1-b]quinazoline-2-carboxylic acid (CAS 436088-43-6)
- N'-[(1Z)-(4-Methylphenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 477864-08-7)
- 2-(1-(2-Nitrophenyl)-1H-pyrazol-5-yl)thiazole (CAS 1269294-02-1)
- thieno[2,3-c]pyridine-4-carboxylic acid (CAS 1554074-84-8)
- 3-(5-Methyl-1,3,4-oxadiazol-2-yl)propan-1-amine (CAS 1017131-98-4)
- 1-(3-Chloro-4-methoxyphenyl)-5-propyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1329414-35-8)
- 2-Bromo-4-(methylsulfonyl)-6-nitrophenol (CAS 20951-41-1)
- tert-Butyl 2-bromo-4-methyl-1H-indole-1-carboxylate (CAS 1881328-24-0)
- 1-(2,3-Dichloro-6-nitrophenyl)methanamine hydrochloride (1:1) 147477-03-0 (CAS 147477-03-0)
- 6-(2-Chloropropanoyl)-2,4-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 878617-65-3)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
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