Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate CAS 391-02-6
| CAS No. | 391-02-6 |
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 391-02-6), molecular formula C13H10F3NO3 and molecular weight 285.22 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 4-hydroxy-6-(trifluoromethyl)quinoline-2-carboxylate (CAS 1352935-29-5)
- N-Hydroxy-4-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzamide (CAS 1706457-30-8)
- 2-Ethyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-70-6)
- 4-(((4-Hydroxy-2-methylphenyl)imino)methyl)-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 338403-32-0)
- Ethyl 4-hydroxy-5-(trifluoromethyl)quinoline-3-carboxylate (CAS 56881-18-6)
- Ethyl 4-Hydroxy-6-(trifluoromethyl)quinoline-3-carboxylate (CAS 26893-12-9)
- Ethyl 4-Hydroxy-8-(trifluoromethyl)-3-quinolinecarboxylate (CAS 23851-84-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(ethyl(methyl)amino)thiophen-2-yl)boronate (CAS 2223006-29-7)
Recommended Standards
- Ethyl 4-oxo-6-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate (CAS 71083-01-7)
- Ethyl 2-cyano-3-(3-(trifluoromethoxy)phenyl)acrylate (CAS 773089-44-4)
- Ethyl 4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate (CAS 71083-04-0)
- benzyl 3-methyl-5-(trifluoromethyl)isoxazole-4-carboxylate (CAS 256488-36-5)
- 8-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 258532-71-7)
- sulfaguanidine-d4 (CAS CATO-CCAD301263)
- 3-(2-Methoxyphenyl)-N-(2-(thiophen-2-yl)ethyl)-1H-pyrazole-5-carboxamide (CAS 1240312-09-7)
- 3-Amino-4-chlorobenzoic acid 2-dodecyloxy-1-methyl-2-oxoethyl ester (CAS 63966-96-1)
- 2-Mesitylacetyl chloride (CAS 52629-46-6)
- 1187168-99-5 2-Methyl-4-(4-propoxybenzoyl)pyridine MFCD13153310 (CAS 1187168-99-5)
- 2-Amino-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)propanoic acid (CAS 1104624-49-8)
- N-{2-[2-(sec-Butyl)phenoxy]propyl}-2,4,6-trimethylaniline (CAS 1040688-55-8)
- 2-(4-tert-butyl-2,6-dimethylphenyl)ethanamine (CAS 93720-89-9)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
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