(E)-3-(3,4-dimethoxyphenyl)-N-((2-fluoro-4-methylphenyl)carbamothioyl)acrylamide CAS 338403-77-3
| CAS No. | 338403-77-3 |
| Molecular Formula | C19H19FN2O3S |
| Molecular Weight | 374.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (E)-3-(3,4-dimethoxyphenyl)-N-((2-fluoro-4-methylphenyl)carbamothioyl)acrylamide (C19H19FN2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(E)-3-(3,4-dimethoxyphenyl)-N-((2-fluoro-4-methylphenyl)carbamothioyl)acrylamide (CAS 338403-77-3), molecular formula C19H19FN2O3S and molecular weight 374.43 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-3-(3,4-dimethoxyphenyl)-N-((2-fluoro-4-methylphenyl)carbamothioyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19FN2O3S |
| Molecular Weight | 374.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
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Recommended Standards
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- (R)-2-Amino-4-oxo-4-(tritylamino)butanoic acid (CAS 19892-86-5)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 256457-60-0)
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- (R)-2-(6-Benzhydrylpyridin-2-yl)-4-(tert-butyl)-4,5-dihydrooxazole (CAS 2757083-50-2)
- 3-(Cyclopropylmethoxy)-4-isopropylphenol (CAS 1243280-57-0)
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- [3-Fluoro-4-methyl-2-(methylsulfanyl)phenyl]methanol (CAS 2145093-92-9)
- N-[2-(Phenethyloxy)benzyl]-3-(3-phenylpropoxy)aniline (CAS 1040691-00-6)
- 1-(1-Benzylpiperidin-4-yl)piperazine trihydrochloride (CAS 1956334-81-8)
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