7-(2,4-Dichlorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 338403-87-5
| CAS No. | 338403-87-5 |
| Molecular Formula | C12H8Cl2N4S |
| Molecular Weight | 311.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-(2,4-Dichlorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine.
CATO supplies 7-(2,4-Dichlorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338403-87-5), a certified reference material (molecular formula C12H8Cl2N4S, MW 311.19 g/mol) for analytical method development and quality control.
The molecular framework of 7-(2,4-Dichlorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine (C12H8Cl2N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(2,4-Dichlorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N4S |
| Molecular Weight | 311.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 4-(5-(2,4-Dichlorophenyl)furan-2-yl)thiazol-2-amine (CAS 338785-87-8)
- 4-(5-(3,4-Dichlorophenyl)furan-2-yl)thiazol-2-amine (CAS 886494-24-2)
- 7-(3,4-Dichlorophenyl)-2-(methylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338394-80-2)
- 1-(3,4-Dichlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)urea (CAS 106472-36-0)
- 1-{[5-(3,4-dichlorophenyl)-1,2-oxazol-3-yl]methyl}piperidine (CAS 343374-62-9)
- (3,5-Dichlorophenyl)(3,4-dimethoxyphenyl)methanone (CAS 116412-97-6)
- Methyl 3-(3,5-dichlorophenyl)-5-methoxybenzoate (CAS 1820739-86-3)
- (3,4-Dichlorophenyl)(3,4-dimethoxyphenyl)methanone (CAS 92436-56-1)
Recommended Standards
- 4-Chloro-3-(2-chlorophenyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine (CAS 864300-84-5)
- 4'-Bromo-3-(methylsulfonyl)-1,1'-biphenyl (CAS 904086-03-9)
- N-Benzyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-amine (CAS 2077892-14-7)
- 3-Bromo-5-(thiophen-2-ylsulfonyl)-1,2,4-thiadiazole (CAS 1000574-92-4)
- 3-Bromo-5-chloro-2-fluoroaniline (CAS 1269232-95-2)
- Ruthenium, [(1,2,3,4,5-η)-2,4-dimethyl-2,4-pentadien-1-yl][(1S)-1-[(1R)-1-(diphenylphosphino-κP)ethyl]-2-[2-(diphenylphosphino-κP)phenyl]ferrocene]iodo- (CAS 1021494-84-7)
- 953905-37-8 2-[4-(3-Methylbutoxy)phenyl]ethan-1-amine--hydrogen chloride (1/1) DTXSID40657976 (CAS 953905-37-8)
- 4-Ethoxy-2-(methylthio)-6-(piperidin-2-ylmethoxy)pyrimidine hydrochloride (CAS 1353980-63-8)
- 2,3-Dimethylbenzene-1-carbonyl chloride (CAS 21900-46-9)
- 1-(4-Iodophenyl)-2-(methylthio)ethan-1-one (CAS 1179822-13-9)
- Methyl (2S,3S)-3-hydroxypiperidine-2-carboxylate (CAS 1932624-97-9)
- (Hexahydrocyclopenta[c]pyrrol-3a(1h)-yl)methanol (CAS 1286088-27-4)
- Methanandamide (CAS 150314-39-9)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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